X-Linked adrenoleukodystrophy (ALD) is a peroxisomal metabolic disorder with a highly
complex clinical presentation. ALD is caused by mutations in the ABCD1 gene, which leads …

X-linked adrenoleukodystrophy (X-ALD) is the most frequent peroxisomal disease. The two
main clinical phenotypes of X-ALD are adrenomyeloneuropathy (AMN) and inflammatory …

X-linked adrenoleukodystrophy is the most common peroxisomal disorder. The disease is
caused by mutations in the ABCD1 gene that encodes the peroxisomal transporter of very …

X-linked adrenoleukodystrophy (X-ALD) is caused by mutations in the ABCD1 gene
encoding a peroxisomal ABC transporter. In this review, we compare estimates of incidence …

ATP-binding cassette (ABC) transporters belong to one of the largest families of membrane
proteins, and are present in almost all living organisms from eubacteria to mammals. They …

The transition from seed to seedling is an important step in the life cycle of plants, which is
fuelled primarily by the breakdown of triacylglycerol (TAG) in 'oilseed'species. TAG is stored …

Peroxisomes contribute to several crucial metabolic processes such as β-oxidation of fatty
acids, biosynthesis of ether phospholipids and metabolism of reactive oxygen species …

ATP-binding cassette (ABC) transporters constitute one of the largest superfamilies of
conserved proteins from bacteria to mammals. In humans, three members of this family are …

The progressive neurometabolic disorder X-linked adrenoleukodystrophy (ALD) is caused
by pathogenic variants in the ABCD1 gene, which encodes the peroxisomal ATP-binding …

Peroxisomes are arguably the most biochemically versatile of all eukaryotic organelles.
Their metabolic functions vary between different organisms, between different tissue types of …