S Sharifian, A Homaei, E Kamrani, T Etzerodt… - International journal of …, 2020 - Elsevier
The monooxygenase enzymes, cytochrome P450s (CYPs), are ubiquitous in their presence and versatile in their functions. They are indispensable for hormone synthesis, dietary …
Cadmium (Cd) is a non-essential toxic heavy metal with the potential to induce oxidative stress. Cd toxicity and its capacity for accumulation in aquatic habitats have earned its …
JC Otte, AD Schmidt, H Hollert, T Braunbeck - Aquatic Toxicology, 2010 - Elsevier
Endpoints of planar halogenated aromatic hydrocarbon (pHAH) and polycyclic aromatic hydrocarbon (PAH) toxicity are mediated via activation of the aryl hydrocarbon receptor …
Y Fu, M Li, C Liu, JP Qu, WJ Zhu, HJ Xing… - Ecotoxicology and …, 2013 - Elsevier
Chlorpyrifos (CPF) and atrazine (ATR) are the most widely used organophosphate insecticides and triazine herbicides, respectively, worldwide. This study aimed at …
Hypoxia-inducible factor-α (HIF-α) and cytochrome P450 1A (CYP1A) are biomarkers of environmental exposure to hypoxia and organic xenobiotic chemicals that act through the …
RO Kim, BM Kim, DS Hwang, DWT Au, JH Jung… - … and Physiology Part C …, 2013 - Elsevier
CYP1A is involved in the metabolism of diverse chemicals, including polycyclic aromatic hydrocarbons and alkylated-PAHs, as a first line of detoxification mechanism. First, we …
Knowledge of the complement of cytochrome P450 (CYP) genes is essential to understanding detoxification and bioactivation mechanisms for organic contaminants. We …
SJ Woo, JK Chung - Aquatic Toxicology, 2020 - Elsevier
Cytochrome P450 (CYP) enzymes play important roles in the detoxification and bioactivation of environmental contaminants and are involved in the responses to pollution in fish. In this …
J Zhang, J Yao, R Wang, Y Zhang, S Liu, L Sun… - … et Biophysica Acta (BBA …, 2014 - Elsevier
Abstract Background Cytochrome P450s (CYPs) encode one of the most diverse enzyme superfamily in nature. They catalyze oxidative reactions of endogenous molecules and …