Cytochrome P450 (CYP) in fish

T Uno, M Ishizuka, T Itakura - Environmental toxicology and pharmacology, 2012 - Elsevier
Cytochrome P450 (CYP) enzymes are members of the hemoprotein superfamily, and are
involved in the mono-oxygenation reactions of a wide range of endogenous and exogenous …

New insights on the marine cytochrome P450 enzymes and their biotechnological importance

S Sharifian, A Homaei, E Kamrani, T Etzerodt… - International journal of …, 2020 - Elsevier
The monooxygenase enzymes, cytochrome P450s (CYPs), are ubiquitous in their presence
and versatile in their functions. They are indispensable for hormone synthesis, dietary …

Effect of cadmium exposure on expression of antioxidant gene transcripts in the river pufferfish, Takifugu obscurus (Tetraodontiformes)

JH Kim, JS Rhee, JS Lee, HU Dahms, J Lee… - … and Physiology Part C …, 2010 - Elsevier
Cadmium (Cd) is a non-essential toxic heavy metal with the potential to induce oxidative
stress. Cd toxicity and its capacity for accumulation in aquatic habitats have earned its …

Spatio-temporal development of CYP1 activity in early life-stages of zebrafish (Danio rerio)

JC Otte, AD Schmidt, H Hollert, T Braunbeck - Aquatic Toxicology, 2010 - Elsevier
Endpoints of planar halogenated aromatic hydrocarbon (pHAH) and polycyclic aromatic
hydrocarbon (PAH) toxicity are mediated via activation of the aryl hydrocarbon receptor …

Effect of atrazine and chlorpyrifos exposure on cytochrome P450 contents and enzyme activities in common carp gills

Y Fu, M Li, C Liu, JP Qu, WJ Zhu, HJ Xing… - Ecotoxicology and …, 2013 - Elsevier
Chlorpyrifos (CPF) and atrazine (ATR) are the most widely used organophosphate
insecticides and triazine herbicides, respectively, worldwide. This study aimed at …

Effects of hypoxia exposure on hepatic cytochrome P450 1A (CYP1A) expression in Atlantic croaker: molecular mechanisms of CYP1A down-regulation

MS Rahman, P Thomas - PloS one, 2012 - journals.plos.org
Hypoxia-inducible factor-α (HIF-α) and cytochrome P450 1A (CYP1A) are biomarkers of
environmental exposure to hypoxia and organic xenobiotic chemicals that act through the …

Evaluation of biomarker potential of cytochrome P450 1A (CYP1A) gene in the marine medaka, Oryzias melastigma exposed to water-accommodated fractions (WAFs) …

RO Kim, BM Kim, DS Hwang, DWT Au, JH Jung… - … and Physiology Part C …, 2013 - Elsevier
CYP1A is involved in the metabolism of diverse chemicals, including polycyclic aromatic
hydrocarbons and alkylated-PAHs, as a first line of detoxification mechanism. First, we …

New cytochrome P450 1B1, 1C2 and 1D1 genes in the killifish Fundulus heteroclitus: Basal expression and response of five killifish CYP1s to the AHR agonist …

J Zanette, MJ Jenny, JV Goldstone, BR Woodin… - Aquatic Toxicology, 2009 - Elsevier
Knowledge of the complement of cytochrome P450 (CYP) genes is essential to
understanding detoxification and bioactivation mechanisms for organic contaminants. We …

Cytochrome P450 1 enzymes in black rockfish, Sebastes schlegelii: Molecular characterization and expression patterns after exposure to benzo [a] pyrene

SJ Woo, JK Chung - Aquatic Toxicology, 2020 - Elsevier
Cytochrome P450 (CYP) enzymes play important roles in the detoxification and bioactivation
of environmental contaminants and are involved in the responses to pollution in fish. In this …

The cytochrome P450 genes of channel catfish: their involvement in disease defense responses as revealed by meta-analysis of RNA-Seq data sets

J Zhang, J Yao, R Wang, Y Zhang, S Liu, L Sun… - … et Biophysica Acta (BBA …, 2014 - Elsevier
Abstract Background Cytochrome P450s (CYPs) encode one of the most diverse enzyme
superfamily in nature. They catalyze oxidative reactions of endogenous molecules and …