Genomics of Actinobacteria: Tracing the Evolutionary History of an Ancient Phylum

M Ventura, C Canchaya, A Tauch… - Microbiology and …, 2007 - Am Soc Microbiol
Actinobacteria constitute one of the largest phyla among Bacteria and represent gram-
positive bacteria with a high G+ C content in their DNA. This bacterial group includes …

Biodegradation potential of the genus Rhodococcus

L Martínková, B Uhnáková, M Pátek, J Nešvera… - Environment …, 2009 - Elsevier
A large number of aromatic compounds and organic nitriles, the two groups of compounds
covered in this review, are intermediates, products, by-products or waste products of the …

Biocatalytic conversion of lignin to aromatic dicarboxylic acids in Rhodococcus jostii RHA1 by re-routing aromatic degradation pathways

Z Mycroft, M Gomis, P Mines, P Law, TDH Bugg - Green chemistry, 2015 - pubs.rsc.org
The heteropolymer lignin represents an untapped resource for production of renewable
aromatic chemicals, if efficient depolymerisation methods can be developed. In this work, the …

Discovery and characterization of a prevalent human gut bacterial enzyme sufficient for the inactivation of a family of plant toxins

N Koppel, JE Bisanz, ME Pandelia, PJ Turnbaugh… - Elife, 2018 - elifesciences.org
Although the human gut microbiome plays a prominent role in xenobiotic transformation,
most of the genes and enzymes responsible for this metabolism are unknown. Recently, we …

Microbial hosts for metabolic engineering of lignin bioconversion to renewable chemicals

TDH Bugg, JJ Williamson, F Alberti - Renewable and Sustainable Energy …, 2021 - Elsevier
This review discusses the use of engineered microbes for bioconversion of lignin from plant
biomass to produce renewable chemicals. Existing bacterial hosts for lignin bioconversion …

Assembly in vitro of Rhodococcus jostii RHA1 encapsulin and peroxidase DypB to form a nanocompartment

R Rahmanpour, TDH Bugg - The FEBS journal, 2013 - Wiley Online Library
Rhodococcus jostii RHA1 peroxidase DypB has been recently identified as a bacterial lignin
peroxidase. The dypB gene is cotranscribed with a gene encoding an encapsulin protein …

Metabolic engineering of Rhodococcus jostii RHA1 for production of pyridine-dicarboxylic acids from lignin

EM Spence, L Calvo-Bado, P Mines, TDH Bugg - Microbial cell factories, 2021 - Springer
Genetic modification of Rhodococcus jostii RHA1 was carried out in order to optimise the
production of pyridine-2, 4-dicarboxylic acid and pyridine-2, 5-dicarboxylic acid bioproducts …

Current status, challenges and prospects for lignin valorization by using Rhodococcus sp.

W Jiang, H Gao, J Sun, X Yang, Y Jiang, W Zhang… - Biotechnology …, 2022 - Elsevier
Lignin represents the most abundant renewable aromatics in nature, which has complicated
and heterogeneous structure. The rapid development of biotransformation technology has …

Plasmid rolling‐circle replication

JA Ruiz-Masó, C Machón… - … : Biology and Impact …, 2015 - Wiley Online Library
The main features that characterize rolling‐circle replication (RCR)(see Fig. 1A) derive from
its singular initiation mechanism, which relies on the sequence‐specific cleavage, at the nick …

Vanillin catabolism in Rhodococcus jostii RHA1

HP Chen, M Chow, CC Liu, A Lau, J Liu… - Applied and …, 2012 - Am Soc Microbiol
Genes encoding vanillin dehydrogenase (vdh) and vanillate O-demethylase (vanAB) were
identified in Rhodococcus jostii RHA1 using gene disruption and enzyme activities. During …