The discovery of vaccine antigens through whole genome sequencing (WGS) contrasts with
the classical hypothesis-driven laboratory-based analysis of microbes to identify …

Epidemiology of community-acquired bacterial meningitis : Current Opinion in Infectious
Diseases Epidemiology of community-acquired bacterial meningitis : Current Opinion in …

Abstract Background In September 2015, the four-component, protein-based meningococcal
serogroup B vaccine (4CMenB; Bexsero) became available for private purchase in Spain …

Abstract Background The Meningococcal Antigen Typing System (MATS) was developed to
identify meningococcus group B strains with a high likelihood of being covered by the …

The 4-component meningococcal serogroup B (MenB) vaccine, 4CMenB, the first broadly
protective, protein-based MenB vaccine to be licensed, is now registered in more than 50 …

As microbial genomics makes increasingly important contributions to clinical and public
health microbiology, the interpretation of whole-genome sequence data by nonspecialists …

Introduction: The successful development of two broadly protective vaccines targeting
Neisseria meningitidis serogroup B (MenB); 4CMenB and rLP2086, is the most significant …

Summary Background The UK introduced 4CMenB—a multicomponent vaccine against
serogroup B meningococcal disease—into the national infant immunisation programme in …

Serogroup B meningococci (MenB) remain a prominent cause of invasive meningococcal
disease (IMD). The protein-based multicomponent 4CMenB and the bivalent MenB-FHbp …

Invasive meningococcal disease (IMD) caused by Neisseria meningitidis is characterized by
high mortality and morbidity. While IMD incidence peaks in both infants and …