The Golgi apparatus plays a central role in cell homeostasis, not only in processing and
maturing newly synthesized proteins and lipids but also in orchestrating their sorting …

In this review article, we summarize current knowledge on peroxisome biogenesis/functions
and the role that small GTPases may play in these processes. Precise intracellular …

This study aims to employ a pulsed electric field (PEF) treatment for the biocompatible (non-
destructive) extraction of proteins from living cells of the green microalga Haematococcus …

Mutation of C9ORF72 is the most common genetic cause of amyotrophic lateral sclerosis
(ALS) and frontal temporal degeneration (FTD), which is attributed to both a gain and loss of …

Background Adhesion molecules distributed on the cell-surface depends upon their
dynamic trafficking that plays an important role during cancer progression. ADP-ribosylation …

Clathrin mediated endocytosis is one pathway for internalization of extracellular nano
materials into cells [1, 2]. In this pathway, proteins attached to receptors and the internalized …

Purpose To test the hypothesis that autophagy dysfunction is involved in exfoliation
syndrome (XFS), a systemic disorder of extracellular elastic matrices that causes a distinct …

Practice of tumor-targeted suicide gene therapy is hampered by unsafe and low efficient
delivery of plasmid DNA (pDNA). Using HIV-Tat-derived peptide (Tat) to non-covalently form …

Background Invadopodia facilitate cancer cell extravasation, but the molecular mechanism
whereby invadopodia-specific proteases such as MT1-MMP are called to invadopodia is …

Ras is a molecular switch cycling between an active, GTP-bound and an inactive, GDP-
bound state. Mutations in Ras, mostly affecting the off-switch, are found in many human …