Past, present, and future perspectives on computer-aided drug design methodologies
The application of computational approaches in drug discovery has been consolidated in
the last decades. These families of techniques are usually grouped under the common …
the last decades. These families of techniques are usually grouped under the common …
[HTML][HTML] Characterization of SARS-CoV-2 recombinants and emerging Omicron sublineages
Y Wang, Y Long, F Wang, C Li, W Liu - International journal of …, 2023 - ncbi.nlm.nih.gov
Abstract The SARS-CoV-2 Omicron is currently the predominant circulating variant in the
COVID-19 pandemic. The dominating Omicron sublineages respond to host immune …
COVID-19 pandemic. The dominating Omicron sublineages respond to host immune …
Impaired VEGF-A-mediated neurovascular crosstalk induced by SARS-CoV-2 spike protein: a potential hypothesis explaining long COVID-19 symptoms and COVID …
R Talotta - Microorganisms, 2022 - mdpi.com
Long coronavirus disease-19 (COVID-19) is a newly discovered syndrome characterized by
multiple organ manifestations that persist for weeks to months, following the recovery from …
multiple organ manifestations that persist for weeks to months, following the recovery from …
Ghosts of the past: Elemental composition, biosynthesis reactions and thermodynamic properties of Zeta P. 2, Eta B. 1.525, Theta P. 3, Kappa B. 1.617. 1, Iota B. 1.526 …
From the perspectives of molecular biology, genetics and biothermodynamics, SARS-CoV-2
is the among the best characterized viruses. Research on SARS-CoV-2 has shed a new …
is the among the best characterized viruses. Research on SARS-CoV-2 has shed a new …
Lessons learnt from COVID-19: computational strategies for facing present and future pandemics
Since its outbreak in December 2019, the COVID-19 pandemic has caused the death of
more than 6.5 million people around the world. The high transmissibility of its causative …
more than 6.5 million people around the world. The high transmissibility of its causative …
A Repurposed Drug Interferes with Nucleic Acid to Inhibit the Dual Activities of Coronavirus Nsp13
N Soper, I Yardumian, E Chen, C Yang… - ACS Chemical …, 2024 - ACS Publications
The recent pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-
CoV-2) highlighted a critical need to discover more effective antivirals. While therapeutics for …
CoV-2) highlighted a critical need to discover more effective antivirals. While therapeutics for …
A therapy for suppressing canonical and noncanonical SARS-CoV-2 viral entry and an intrinsic intrapulmonary inflammatory response
SL Leibel, RN McVicar, R Murad, EM Kwong… - Proceedings of the …, 2024 - pnas.org
The prevalence of “long COVID” is just one of the conundrums highlighting how little we
know about the lung's response to viral infection, particularly to syndromecoronavirus-2 …
know about the lung's response to viral infection, particularly to syndromecoronavirus-2 …
Performance analysis of serodiagnostic tests to characterize the incline and decline of the individual humoral immune response in COVID-19 patients: impact on …
R von Possel, B Menge, C Deschermeier, C Fritzsche… - Viruses, 2024 - mdpi.com
Serodiagnostic tests for antibody detection to estimate the immunoprotective status
regarding SARS-CoV-2 support diagnostic management. This study aimed to investigate the …
regarding SARS-CoV-2 support diagnostic management. This study aimed to investigate the …
Comparing severe COVID-19 outcomes of first and second/third waves: a prospective single-Centre cohort study of health-related quality of life and pulmonary …
P Darlington, M Roël, M Cronhjort, G Hanna… - BMJ open, 2023 - bmjopen.bmj.com
Objective We aimed to compare long-term outcomes in intensive care unit (ICU) survivors
between the first and second/third waves of the COVID-19 pandemic. More specifically, to …
between the first and second/third waves of the COVID-19 pandemic. More specifically, to …
Evaluating the transmission feasibility of SARS-CoV-2 Omicron (B. 1.1. 529) variant to 143 mammalian hosts: insights from S protein RBD and host ACE2 interaction …
In comparison to previously known severe respiratory syndrome coronavirus 2 (SARS-CoV-
2) variants, the newly emerged Omicron (B. 1.1. 529) variant shows higher infectivity in …
2) variants, the newly emerged Omicron (B. 1.1. 529) variant shows higher infectivity in …