Analgesia and sedation in patients with ARDS

G Chanques, JM Constantin, JW Devlin, EW Ely… - Intensive care …, 2020 - Springer
Abstract Acute Respiratory Distress Syndrome (ARDS) is one of the most demanding
conditions in an Intensive Care Unit (ICU). Management of analgesia and sedation in ARDS …

The ABCDEF bundle in critical care

A Marra, EW Ely, PP Pandharipande… - Critical care …, 2017 - criticalcare.theclinics.com
With more than 4 million intensive care unit (ICU) admissions per year in the United States,
there is increasing recognition of the long-term consequences of ICU care on the physical …

Weaning from mechanical ventilation in intensive care units across 50 countries (WEAN SAFE): a multicentre, prospective, observational cohort study

T Pham, L Heunks, G Bellani, F Madotto… - The Lancet …, 2023 - thelancet.com
Background Current management practices and outcomes in weaning from invasive
mechanical ventilation are poorly understood. We aimed to describe the epidemiology …

Clinical practice guidelines for the prevention and management of pain, agitation/sedation, delirium, immobility, and sleep disruption in adult patients in the ICU

JW Devlin, Y Skrobik, C Gélinas… - Critical care …, 2018 - journals.lww.com
Objective: To update and expand the 2013 Clinical Practice Guidelines for the Management
of Pain, Agitation, and Delirium in Adult Patients in the ICU. Design:

Early sedation with dexmedetomidine in critically ill patients

Y Shehabi, BD Howe, R Bellomo… - … England Journal of …, 2019 - Mass Medical Soc
Background Dexmedetomidine produces sedation while maintaining a degree of
arousability and may reduce the duration of mechanical ventilation and delirium among …

Early, goal-directed mobilisation in the surgical intensive care unit: a randomised controlled trial

SJ Schaller, M Anstey, M Blobner, T Edrich, SD Grabitz… - The Lancet, 2016 - thelancet.com
Background Immobilisation predicts adverse outcomes in patients in the surgical intensive
care unit (SICU). Attempts to mobilise critically ill patients early after surgery are frequently …

Surviving sepsis campaign: international guidelines for management of sepsis and septic shock: 2016

A Rhodes, LE Evans, W Alhazzani, MM Levy… - Intensive care …, 2017 - Springer
Objective To provide an update to “Surviving Sepsis Campaign Guidelines for Management
of Sepsis and Septic Shock: 2012”. Design A consensus committee of 55 international …

The ABCDEF bundle: science and philosophy of how ICU liberation serves patients and families

EW Ely - Critical care medicine, 2017 - journals.lww.com
Over the past 20 years, critical care has matured in a myriad of ways resulting in dramatically
higher survival rates for our sickest patients. For millions of new survivors comes de novo …

[HTML][HTML] Septic-associated encephalopathy: a comprehensive review

A Mazeraud, C Righy, E Bouchereau, S Benghanem… - …, 2020 - Elsevier
Septic-associated encephalopathy (SAE) is a key manifestation of sepsis, ranging from
delirium to coma and occurring in up to 70% of patients admitted to the ICU. SAE is …

Pharmacological and non-pharmacological interventions to prevent delirium in critically ill patients: a systematic review and network meta-analysis

LD Burry, W Cheng, DR Williamson, NK Adhikari… - Intensive care …, 2021 - Springer
Purpose To compare the effects of prevention interventions on delirium occurrence in
critically ill adults. Methods MEDLINE, Embase, PsychINFO, CINAHL, Web of Science …