The promise of nanotechnology in personalized medicine

MA Alghamdi, AN Fallica, N Virzì… - Journal of personalized …, 2022 - mdpi.com
Both personalized medicine and nanomedicine are new to medical practice. Nanomedicine
is an application of the advances of nanotechnology in medicine and is being integrated into …

Bridging smart nanosystems with clinically relevant models and advanced imaging for precision drug delivery

Q Zhou, Q Liu, Y Wang, J Chen, O Schmid… - Advanced …, 2024 - Wiley Online Library
Intracellular delivery of nano‐drug‐carriers (NDC) to specific cells, diseased regions, or
solid tumors has entered the era of precision medicine that requires systematic knowledge …

Nuclear Transport of the Molecular Drug via Nanocarrier-Based Nonendocytic Cellular Uptake

AK Sarkar, S Shaw, H Arora, P Seth… - ACS Applied Materials & …, 2023 - ACS Publications
Although subcellular targeting can enhance the therapeutic performance of most drugs,
such targeting requires appropriate carrier-based delivery that can bypass …

Environmental nanoparticles reach human fetal brains

L Calderón-Garcidueñas, ÁA Pérez-Calatayud… - Biomedicines, 2022 - mdpi.com
Anthropogenic ultrafine particulate matter (UFPM) and industrial and natural nanoparticles
(NPs) are ubiquitous. Normal term, preeclamptic, and postconceptional weeks (PCW) 8–15 …

Cytotoxicity of ZnO nanoparticles under dark conditions via oxygen vacancy dependent reactive oxygen species generation

A Biswas, U Kar, NR Jana - Physical Chemistry Chemical Physics, 2022 - pubs.rsc.org
The antimicrobial and cytotoxic effects of zinc oxide nanomaterials are popularly thought to
be occurring due to zinc ion leaching, but the exact mechanism of cytotoxicity is …

Inhibiting protein aggregation by small molecule-based colloidal nanoparticles

K Debnath, AK Sarkar, NR Jana… - Accounts of materials …, 2021 - ACS Publications
Conspectus Protein aggregation is associated with different human diseases such as
Alzheimer's, Huntington's, Parkinson's, diabetes type II, and cataracts. Currently no effective …

Tin-loaded mesoporous silica nanoparticles: Antineoplastic properties and genotoxicity assessment

PC Choudante, SK Nethi, D Diaz-Garcia, S Prashar… - Biomaterials …, 2022 - Elsevier
Nanotechnology has immensely advanced the field of cancer diagnostics and treatment by
introducing potential delivery vehicles as carriers for drugs or therapeutic agents. In due …

Arginine Surface Density of Nanoparticles Controls Nonendocytic Cell Uptake and Autophagy Induction

R Ray, S Ghosh, A Maity, NR Jana - ACS Applied Materials & …, 2024 - ACS Publications
Nonendocytic cell uptake of nanomaterials is challenging, which requires specific surface
chemistry and smaller particle size. Earlier works have shown that an arginine-terminated …

Direct cellular delivery of exogenous genetic material and protein via colloidal nano-assemblies with biopolymer

AK Sarkar, K Debnath, H Arora, P Seth… - … Applied Materials & …, 2022 - ACS Publications
Direct cytosolic delivery of large biomolecules that bypass the endocytic pathways is a
promising strategy for therapeutic applications. Recent works have shown that small …

From cell membrane to endoplasmic reticulum: Tunable lipid membrane imaging by regulating the lipophilicity and internalization of carbon dots

Y Xing, J Li, H Leng, Y Zhang, E Shuang… - Chemical Engineering …, 2024 - Elsevier
The interactions between various organelles play a crucial role on cellular activity, and the
design and construction of multi-organelle fluorescent probes is of great challenges. Herein …