Amino acids/peptides conjugated heterocycles: A tool for the recent development of novel therapeutic agents

M Wang, KP Rakesh, J Leng, WY Fang, L Ravindar… - Bioorganic …, 2018 - Elsevier
Amino acids/peptide conjugated heterocycles represent an important class of therapeutical
agents. Biologically active heterocycles are conjugated with amino acids or peptides to …

Synthesis, Structural Studies, and α-Glucosidase Inhibitory, Antidiabetic, and Antioxidant Activities of 2,3-Dihydroquinazolin-4(1H)-ones Derived from Pyrazol-4 …

A Barmak, K Niknam, G Mohebbi - ACS omega, 2019 - ACS Publications
A series of new quinazoline derivatives were designed and synthesized via a one-pot
condensation reaction between isatoic anhydride and aromatic aldehydes with anilines …

Synthesis and Antimicrobial Activity of 3-(1, 3, 4-Oxadiazol-2-yl) quinazolin-4 (3H)-ones

NB Patel, JC Patel - Scientia pharmaceutica, 2010 - mdpi.com
In attempt to find new pharmacologically active molecules, we report here the synthesis and
in vitro antimicrobial activity of various 3-(1, 3, 4-oxadiazol-2-yl)-quinazolin-4 (3 H)-ones …

[HTML][HTML] Synthesis and antimicrobial activity of Schiff bases and 2-azetidinones derived from quinazolin-4 (3H)-one

NB Patel, JC Patel - Arabian Journal of Chemistry, 2011 - Elsevier
A series of 2-oxo-azetidinyl-quinazolin-4 (3H)-ones 5a–k have been synthesized from Schiff
bases 4a–k. Schiff bases were synthesized by the condensation reaction of compound 3 …

Synthesis and characterization of quinazoline derivatives: search for hybrid molecule as diuretic and antihypertensive agents

MU Rahman, A Rathore, AA Siddiqui… - Journal of Enzyme …, 2014 - Taylor & Francis
To explore the pharmacological and structure–activity relationship of a series of N-
substituted-(4-oxo-2-substituted-phenylquinazolin-3-(4H)-yl), substituted benzene …

Synthesis, crystal and molecular structure, and characterization of 2-((2-aminopyridin-3-yl) methylene)-N-ethylhydrazinecarbothioamide using spectroscopic (1H and …

K Ramaiah, K Srishailam, KL Reddy, BV Reddy… - Journal of Molecular …, 2019 - Elsevier
Abstract 2-((2-aminopyridin-3-yl) methylene)-N-ethylhydrazinecarbothioamide was
synthesized. It was characterized by making elemental analysis, assisted by experimental 1 …

Synthesis and evaluation of molecular structure from torsional scans, study of molecular characteristics using spectroscopic and DFT methods of some …

K Srishailam, K Ramaiah, KL Reddy, BV Reddy… - Chemical Papers, 2021 - Springer
Abstract Synthesis of 2-((2-aminopyridin-3-yl) methylene) hydrazinecarbothioamide (APHT)
was attempted. Elemental analysis and NMR spectra were used to ascertain its formation …

Synthesis, characterization, antimicrobial studies and corrosion inhibition potential of 1, 8-dimethyl-1, 3, 6, 8, 10, 13-hexaazacyclotetradecane: experimental and …

HU Nwankwo, CN Ateba, LO Olasunkanmi… - Materials, 2016 - mdpi.com
The macrocylic ligand, 1, 8-dimethyl-1, 3, 6, 8, 10, 13-hexaazacyclotetradecane (MHACD)
was synthesized by the demetallation of its freshly synthesized Ni (II) complex (NiMHACD) …

Novel 4 (3H)-quinazolinones containing biologically active thiazole, pyridinone and chromene of expected antitumor and antifungal activities

KAHM El-Bayouki, WM Basyouni… - European Journal of …, 2011 - eurjchem.com
Novel 4 (3 H)-quinazolinone derivatives with biologically active moieties were synthesized.
Reactions of 2-cyano-N-(6-iodo-2-methyl-4-oxoquinazolin-3 (4 H)-yl) acetamide with carbon …

Design and evaluation of new hybrid pharmacophore quinazolino-tetrazoles as anticonvulsant strategy

S Malik, SA Khan - Medicinal Chemistry Research, 2014 - Springer
The anticonvulsant study of 25 newly synthesized quinazolin-4 (3 H)-one substituted 1 H
and 2 H-tetrazoles (6a–6d, 7a–7b, 8a–8i, 8a′–8i′) was executed. The study employing …