Tumour progression is dependent on the interaction between tumour cells and cells of the
surrounding microenvironment. The tumour is a dynamic milieu consisting of various cell …

Simple Summary For the research and development of drug discovery, it is of prime
importance to construct the three-dimensional (3D) tissue models in vitro. To this end, the …

Mesenchymal stem cells (MSCs) are a major component of the tumor microenvironment
(TME) and play a key role in promoting tumor progression. The tumor uses exosomes to co …

Malignant cells drive the generation of a desmoplastic and immunosuppressive tumor
microenvironment. Cancer-associated stromal cells (CASC) are a heterogeneous …

Mesenchymal stem cells (MSCs) are of particular interest for the treatment of immune-
related diseases owing to their immunosuppressive properties. In this study, we aimed to …

Mesenchymal stem or stromal cells (MSCs) are pluripotent cells implicated in a broad range
of physiological events, including organogenesis and maintenance of tissue homeostasis as …

Pancreatic tumors are known to harbor an abundant and highly desmoplastic stroma.
Among the various cell types that reside within tumor stroma, cancer-associated fibroblasts …

Increasing evidence indicates that the tumor microenvironment appears to play an
increasingly important role in cancer progression and therapeutic resistance. Several types …

The liver has the ability to repair itself after injury; however, a variety of pathological changes
in the liver can affect its ability to regenerate, and this could lead to liver failure …

Abstract Background Mesenchymal stromal cells (MSCs) are a promising therapy for
preventing chronic Graft-Versus-Host Disease (cGVHD) due to their potent …