Review on the cellular mechanisms of low-level laser therapy use in oncology

SY Tam, VCW Tam, S Ramkumar, ML Khaw… - Frontiers in …, 2020 - frontiersin.org
Photobiomodulation (PBM) using low-level laser therapy (LLLT) is a treatment that is
increasingly used in oncology. Studies reported enhancement of wound healing with …

Experimental and clinical applications of red and near-infrared photobiomodulation on endothelial dysfunction: A review

E Colombo, A Signore, S Aicardi, A Zekiy, A Utyuzh… - Biomedicines, 2021 - mdpi.com
Background: Under physiological conditions, endothelial cells are the main regulator of
arterial tone homeostasis and vascular growth, sensing and transducing signals between …

Photobiomodulation and oxidative stress: 980 nm diode laser light regulates mitochondrial activity and reactive oxygen species production

A Amaroli, C Pasquale, A Zekiy… - Oxidative Medicine …, 2021 - Wiley Online Library
Photobiomodulation with 808 nm laser light electively stimulates Complexes III and IV of the
mitochondrial respiratory chain, while Complexes I and II are not affected. At the wavelength …

[HTML][HTML] Role of opsins and light or heat activated transient receptor potential ion channels in the mechanisms of photobiomodulation and infrared therapy

SK Sharma, S Sardana, MR Hamblin - Journal of Photochemistry and …, 2023 - Elsevier
Photobiomodulation (otherwise known as low level light therapy) is an emerging approach
for treating many diseases and conditions such as pain, inflammation, wound healing, brain …

Photobiomodulation and nitric oxide signaling

S Kashiwagi, A Morita, S Yokomizo, E Ogawa, E Komai… - Nitric Oxide, 2023 - Elsevier
Nitric oxide (NO) is a well-known gaseous mediator that maintains vascular homeostasis.
Extensive evidence supports that a hallmark of endothelial dysfunction, which leads to …

A narrative review on oral and periodontal bacteria Microbiota photobiomodulation, through visible and near-infrared light: From the origins to modern therapies

A Amaroli, S Ravera, A Zekiy, S Benedicenti… - International Journal of …, 2022 - mdpi.com
Photobiomodulation (PBM) consists of a photon energy transfer to the cell, employing non-
ionizing light sources belonging to the visible and infrared spectrum. PBM acts on some …

[HTML][HTML] Photobiomodulation therapy reduces acute pain and inflammation in mice

GR Pigatto, CS Silva, NA Parizotto - Journal of Photochemistry and …, 2019 - Elsevier
Photobiomodulation (PBM) is a therapy suggested for the treatment of pain and
inflammation. Different mechanisms have been proposed to explain the analgesic and …

[HTML][HTML] Effects of prenatal photobiomodulation treatment on neonatal hypoxic ischemia in rat offspring

L Yang, Y Dong, C Wu, H Youngblood, Y Li, X Zong… - Theranostics, 2021 - ncbi.nlm.nih.gov
Neonatal hypoxic-ischemic (HI) injury is a severe complication often leading to neonatal
death and long-term neurobehavioral deficits in children. Currently, the only treatment option …

Steering the multipotent mesenchymal cells towards an anti-inflammatory and osteogenic bias via photobiomodulation therapy: How to kill two birds with one stone

A Amaroli, C Pasquale, A Zekiy… - Journal of Tissue …, 2022 - journals.sagepub.com
The bone marrow-derived multipotent mesenchymal cells (MSCs) have captured scientific
interest due to their multi-purpose features and clinical applications. The operational …

[HTML][HTML] Light-induced nitric oxide release in the skin beyond UVA and blue light: red & near-infrared wavelengths

AC Barolet, IV Litvinov, D Barolet - Nitric Oxide, 2021 - Elsevier
Nitric oxide (NO) is omnipresent in the body and synthesized by 3 isoenzymes (nNOS,
eNOS and iNOS), all detected in human skin. NO can be stored in a pool of compounds …