Discovery of major histocompatability complex (MHC) restriction helped in the
understanding of how T-lymphocytes recognize antigens on bacteria, viruses, and tumor …

T cell engineering with T cell receptors (TCR) specific to tumor antigens has become a
breakthrough towards personalized cancer adoptive cell immunotherapy. However, the …

The specificity of the T-cell receptor (TCR) and its interaction with coreceptors play a crucial
role in T-cell passing through developmental checkpoints and, eventually, determine the …

Иммунный ответ на введение клеток аллогенных опухолей сопровождается
возникновением долгоживущих клеток памяти CD8+, способных к быстрой …

A peripheral pool of T lymphocytes consists of several functionally distinct populations of
CD8+ T cells. One of the major surface markers that allow to define different populations of T …

Immune response to allogenic tumor cells is associated with the appearance of long-living
CD8+ memory cells capable of rapid restimulation and lysis of tumor cells in case of …

Молекулы MHC являются наиболее «сильными» трансплантационными антигенами,
прямое взаимодействие с которыми определяет ответ 95-98% клонов Т-клеток …

A peripheral pool of T lymphocytes consists of several functionally distinct populations of
CD8+ T cells. One of the major surface markers that allow to define different populations of T …

Введение. Широкое применение глюкокортикоидов в терапии онкологических,
аутоиммунных и аллергических заболеваний сопряжено с подавлением функций …