Despite extensive preclinical research over the years, a significant gap remains in our
understanding of the specific effects of methamphetamine (METH) and amphetamine …

Rationale Methamphetamine is a highly abused psychostimulant drug and its use remains a
major public health concern worldwide with limited effective treatment options. Accumulative …

Rationale Schizophrenia is associated with prenatal inflammation and/or postnatal stressors
such as drug abuse, resulting in immune-redox dysfunction. Antioxidants may offer …

Methamphetamine (METH) is an illicit psychostimulant that is widely abused. After producing
extreme pleasure, METH abuse leads to negative emotional states during withdrawal in …

During the peripartum period, women are at an increased risk to develop perinatal distress,
presenting as symptoms of depression and/or anxiety. Yet, due to practical and ethical …

Over the past 60 years, a large number of selective neurotoxins were discovered and
developed, making it possible to animal-model a broad range of human neuropsychiatric …

Cognitive dysfunction in depression has recently been given more attention and legitimacy
as a core symptom of the disorder. However, animal investigations of depression-related …

Methamphetamine (METH) is a potent psychostimulant drug with an increasing rate of
abuse over recent years. Depressive-like behaviors are one of the major symptoms patients …

Background: Methamphetamine is an addictive stimulant that possesses toxicity in the brain
when taken repeatedly or at higher doses. Methamphetamine neurotoxicity is associated …

Major depressive disorder (MDD) affects a significant number of children and adolescents,
yet treatment options for this population remain very limited. Escitalopram (ESC) is one of …