Synthetic glycans to improve current glycoconjugate vaccines and fight antimicrobial resistance

L Del Bino, KE Østerlid, DY Wu, F Nonne… - Chemical …, 2022 - ACS Publications
Antimicrobial resistance (AMR) is emerging as the next potential pandemic. Different
microorganisms, including the bacteria Acinetobacter baumannii, Clostridioides difficile …

Bacterial biofilm and its role in the pathogenesis of disease

LK Vestby, T Grønseth, R Simm, LL Nesse - Antibiotics, 2020 - mdpi.com
Recognition of the fact that bacterial biofilm may play a role in the pathogenesis of disease
has led to an increased focus on identifying diseases that may be biofilm-related. Biofilm …

Biofilms: Survival and defense strategy for pathogens

A Kumar, A Alam, M Rani, NZ Ehtesham… - International Journal of …, 2017 - Elsevier
Studies on biofilm related infections are gaining prominence owing to their involvement in
majority of clinical infections. Biofilm, considered as a generic mechanism for survival used …

[HTML][HTML] The staphylococcal exopolysaccharide PIA–Biosynthesis and role in biofilm formation, colonization, and infection

HTT Nguyen, TH Nguyen, M Otto - Computational and Structural …, 2020 - Elsevier
Exopolysaccharide is a key part of the extracellular matrix that contributes to important
mechanisms of bacterial pathogenicity, most notably biofilm formation and immune evasion …

Knowledge gaps and research priorities in Staphylococcus aureus mastitis control

P Rainard, G Foucras, JR Fitzgerald… - Transboundary and …, 2018 - Wiley Online Library
This study assessed knowledge gaps and suggested research priorities in the field of
Staphylococcus aureus mastitis. Staphylococcus aureus infecting the mammary gland …

Potential targets for next generation antimicrobial glycoconjugate vaccines

F Micoli, P Costantino, R Adamo - FEMS microbiology reviews, 2018 - academic.oup.com
Cell surface carbohydrates have been proven optimal targets for vaccine development.
Conjugation of polysaccharides to a carrier protein triggers a T-cell-dependent immune …

Mastitis in sheep–The last 10 years and the future of research

AI Gelasakis, VS Mavrogianni, IG Petridis… - Veterinary …, 2015 - Elsevier
Bacterial mastitis is a significant welfare and financial problem in sheep flocks. This paper
reviews the recently published literature, including publications that highlight the …

The role of biofilms in the pathogenesis of animal bacterial infections

LL Nesse, AM Osland, LK Vestby - Microorganisms, 2023 - mdpi.com
Biofilms are bacterial aggregates embedded in a self-produced, protective matrix. The
biofilm lifestyle offers resilience to external threats such as the immune system …

[HTML][HTML] Invited review: a critical appraisal of mastitis vaccines for dairy cows

P Rainard, FB Gilbert, P Germon, G Foucras - Journal of Dairy Science, 2021 - Elsevier
Infections of the mammary gland remain a frequent disease of dairy ruminants that
negatively affect animal welfare, milk quality, farmer serenity, and farming profitability and …

Biofilm formation in bacterial pathogens of veterinary importance

M Jacques, V Aragon, YDN Tremblay - Animal Health Research …, 2010 - cambridge.org
Bacterial biofilms are structured communities of bacterial cells enclosed in a self-produced
polymer matrix that is attached to a surface. Biofilms protect and allow bacteria to survive …