STUDY QUESTION What clinical practices, patient management strategies and
experimental methods are currently being used to preserve and restore the fertility of …

resubmitted on January 17, 2013; accepted on January 28, 2013 study question: What
issues remain to be solved before fertility preservation and transplantation can be offered to …

Spermatogonial stem cells (SSCs) maintain spermatogenesis throughout a man's life and
may have application for treating some cases of male infertility, including those caused by …

Objective To determine the molecular characteristics of human spermatogonia and optimize
methods to enrich spermatogonial stem cells (SSCs). Design Laboratory study using human …

Abstract Three-dimensional (3D) organoids can serve as an in vitro platform to study cell–
cell interactions, tissue development, and toxicology. Development of organoids with tissue …

As the number of young cancer survivors increases, quality of life after cancer treatment is
becoming an ever more important consideration. According to a report from the American …

Spermatogonial stem cell (SSC) transplantation has been shown to restore fertility in several
species and may have application for treating some cases of male infertility (eg, secondary …

Fertility restoration in patients that survived a hematological cancer during childhood is a
core part of their care pathway. Nonetheless, there might be a risk of contamination of the …

Improved therapies for cancer and other conditions have resulted in a growing population of
long-term survivors. Infertility is an unfortunate side effect of some cancer therapies that …

Male infertility management has made significant progress during the past three decades,
especially after the introduction of intracytoplasmic sperm injection in 1992. However, many …