The IL-17 family of cytokines has emerged over the last two decades as a pleiotropic group
of molecules that function in a wide variety of both beneficial and detrimental (pathological) …

Immunostimulation is recognized as an important contribution in lung fibrosis in some
animal models and patient subsets. With this review, we illustrate an additional scenario …

Ethnopharmacological relevance As a classic prescription of Traditional Chinese Medicine
in Correction on the Errors of Medical Works, Buyang Huanwu Decoction (BYHWD) has a …

Silicosis is characterized by chronic lung inflammation and fibrosis, which are seriously
harmful to human health. Previous research demonstrated that uncontrolled T-helper (Th) …

Silicosis is an inflammatory and fibrotic lung disease caused by inhalation of silica. Th17
cells play a key role in causing silica-induced lung inflammation and fibrosis. Baicalin, a …

CD4+ T cells play an important role in regulating silica‐induced inflammation and fibrosis.
Recent studies showed that Wnt/β‐catenin pathway could modulate the function and the …

Due to roles in immunoregulation and low immunogenicity, mesenchymal stem cells have
been suggested to be potent regulators of the immune response and may represent …

Ethnopharmacological relevance Ligustrum purpurascens YC Yang (Oleaceae) is
traditionally recorded as “Ku Ding Cha”, a kind of functional tea in southern China for about …

Long‐term exposure to crystalline silica leads to silicosis, which is characterized by
persistent lung inflammation and lung fibrosis. Multiple immune cells have been …

Studies on immune response to crystal silica in mammals indicate immune stimulation effect
of environmental parameters including silica or asbestos, but there is no information on this …