The fate of developing T cells is specified by the interaction of their antigen receptors with
self-peptide–MHC complexes that are displayed by thymic antigen-presenting cells (APCs) …

(CVD) in individuals with type 1 diabetes mellitus (T1DM), the pathophysiology underlying
the relationship between cardiovascular events, CVD risk factors, and T1DM is not well …

The heart is an autoimmune-prone organ. It is crucial for the heart to keep injury-induced
autoimmunity in check to avoid autoimmune-mediated inflammatory disease. However, little …

Diabetes mellitus-related cardiomyopathy (DMCMP) was originally described as a dilated
phenotype with eccentric left ventricular (LV) remodelling and systolic LV dysfunction …

Over the past decade, knowledge of the pathogenesis and natural history of type 1 diabetes
has grown substantially, particularly with regard to disease prediction and heterogeneity …

Interest in cardioimmunology has reached new heights as the experimental cardiology field
works to tap the unrealized potential of immunotherapy for clinical care. Within this space is …

Individuals with diabetes mellitus (DM) disclose a higher incidence and a poorer prognosis
of heart failure (HF) than non-diabetic people, even in the absence of other HF risk factors …

The high incidence and poor prognosis of heart failure (HF) patients affected with diabetes
(DM) is in part related to a specific cardiac remodeling currently recognized as diabetic …

Cardiovascular disease (CVD) is highly prevalent in patients with type 1 diabetes (T1D) and
a major cause of mortality. CVD arises earlier in life in T1D patients and is responsible for a …

Immune checkpoint inhibitors (ICIs) attenuate mechanisms of self-tolerance in the immune
system, enabling T cell responses to cancerous tissues and revolutionizing care for cancer …