Independent organelle and organelle—organelle interactions: essential mechanisms for malignant gynecological cancer cell survival

Y Shen, QC Chen, CY Li, FJ Han - Frontiers in Immunology, 2024 - frontiersin.org
Different eukaryotic cell organelles (eg, mitochondria, endoplasmic reticulum, lysosome) are
involved in various cancer processes, by dominating specific cellular activities. Organelles …

Nanomedomics

G Liang, W Cao, D Tang, H Zhang, Y Yu, J Ding… - ACS …, 2024 - ACS Publications
Nanomaterials have attractive physicochemical properties. A variety of nanomaterials such
as inorganic, lipid, polymers, and protein nanoparticles have been widely developed for …

AI-based histopathology image analysis reveals a distinct subset of endometrial cancers

A Darbandsari, H Farahani, M Asadi, M Wiens… - Nature …, 2024 - nature.com
Endometrial cancer (EC) has four molecular subtypes with strong prognostic value and
therapeutic implications. The most common subtype (NSMP; No Specific Molecular Profile) …

[HTML][HTML] Proteogenomics unveils mechanistic insights to precision oncology

Y Dou, L Katsnelson, B Zhang, D Fenyö… - Clinical and …, 2023 - ncbi.nlm.nih.gov
Even though genomics plays a critical role in the development of precision treatments for
cancer, the actual treatments overwhelmingly target proteins, which are responsible for most …

[HTML][HTML] 单细胞测序技术在妇科恶性肿瘤研究中的应用

何奕婷, 祁婉婉, 冯振卿 - 南京医科大学学报(自然科学版), 2024 - jnmu.njmu.edu.cn
摘要妇科恶性肿瘤包括宫颈癌, 卵巢癌, 子宫内膜癌等, 具有高度的异质性, 一旦进入晚期,
预后往往不良. 单细胞测序技术的出现和发展为在单个细胞水平上探究肿瘤发生发展的机制 …

Mutations in cancer-relevant genes are ubiquitous in histologically normal endometrial tissue

D Pandya, S Tomita, MP Rhenals, S Swierczek… - Gynecologic …, 2024 - Elsevier
Abstract Objective Endometrial cancer (EndoCA) is the most common gynecologic cancer
and incidence and mortality rate continue to increase. Despite well-characterized …

[HTML][HTML] Endometrial Carcinoma: A Comprehensive Analysis of Clinical Parameters, Treatment Modalities, and Prognostic Outcomes at a Tertiary Oncology Center in …

KS Balaraj, NM Shanbhag, AB Sumaida, SM Hasnain… - Cureus, 2023 - ncbi.nlm.nih.gov
Background Endometrial carcinoma (EC) remains a pressing global health issue, with a
discernible upsurge in incidence, especially in developed countries. Notably, the United …

Impairment of FBXO31-mediated Ubiquitination of OGT Upregulates O-GlcNAcylation to Advance Endometrial Malignancy

K Yuan, N Zhang, Y Meng, S Mao, H Ni, C Huang… - 2024 - researchsquare.com
Aberrant O-GlcNAc cycling of the cancer proteome is a manifestation of its metabolic
plasticity. As one of the most common cancer of the female genital tract associated with …