Extracellular vesicles in human reproduction in health and disease

C Simon, DW Greening, D Bolumar… - Endocrine …, 2018 - academic.oup.com
Extensive evidence suggests that the release of membrane-enclosed compartments, more
commonly known as extracellular vesicles (EVs), is a potent newly identified mechanism of …

Extracellular vesicles in human milk

Y Hu, J Thaler, R Nieuwland - Pharmaceuticals, 2021 - mdpi.com
Milk supports the growth and development of infants. An increasing number of mostly recent
studies have demonstrated that milk contains a hitherto undescribed component called …

The role of extracellular vesicles from different origin in the microenvironment of head and neck cancers

C Xie, N Ji, Z Tang, J Li, Q Chen - Molecular cancer, 2019 - Springer
The proliferation and metastasis ability of tumors are mediate by the" mutual dialogue"
between cells in the tumor microenvironment (TME). Extracellular vesicles (EVs), mainly …

Compartmentalized profiling of amniotic fluid cytokines in women with preterm labor

G Bhatti, R Romero, GE Rice, W Fitzgerald, P Pacora… - PLoS …, 2020 - journals.plos.org
Objective Amniotic fluid cytokines have been implicated in the mechanisms of preterm labor
and birth. Cytokines can be packaged within or on the surface of extracellular vesicles. The …

Single-particle analysis of tear fluid reveals abundant presence of tissue factor-exposing extracellular vesicles with strong coagulation activity

H Liu, W Yuan, Q Pang, C Xue, X Yan - Talanta, 2022 - Elsevier
Extracellular vesicles (EVs) in easily accessible body fluids have emerged as a promising
source for liquid biopsy. Although tear collection is fast, safe, and noninvasive, EVs of tear …

Therapeutic and pharmacological applications of extracellular vesicles and lipoproteins

K Németh, BM Kestecher, S Ghosal… - British Journal of …, 2024 - Wiley Online Library
In recent years, various approaches have been undertaken to eliminate lipoproteins co‐
isolated with extracellular vesicles, as they were initially regarded as contaminating entities …

[HTML][HTML] Extracellular vesicles from II trimester human amniotic fluid as paracrine conveyors counteracting oxidative stress

G Senesi, L Guerricchio, M Ghelardoni, N Bertola… - Redox Biology, 2024 - Elsevier
Background We previously demonstrated that the human amniotic fluid (hAF) from II
trimester of gestation is a feasible source of stromal progenitors (human amniotic fluid stem …

IFPA Joan Hunt Senior Award in Placentology lecture: Extracellular vesicle signalling and pregnancy

GE Rice, C Salomon - Placenta, 2024 - Elsevier
The field of extracellular vesicle (EV) signalling has the potential to transform our
understanding of maternal-fetal communication and affords new opportunities for non …

Human milk triggers coagulation via tissue factor–exposing extracellular vesicles

Y Hu, L Hell, RA Kendlbacher, N Hajji, C Hau… - Blood …, 2020 - ashpublications.org
Almost a century ago, it was discovered that human milk activates the coagulation system,
but the milk component that triggers coagulation had until now been unidentified. In the …

Extracellular vesicles as markers and mediators of pregnancy complications: gestational diabetes, pre‐eclampsia, preterm birth and fetal growth restriction

R Farrelly, MG Kennedy, R Spencer… - The Journal of …, 2023 - Wiley Online Library
In high income countries, approximately 10% of pregnancies are complicated by pre‐
eclampsia (PE), preterm birth (PTB), fetal growth restriction (FGR) and/or macrosomia …