• An overview of the current understanding of bleeding and thrombosis in cirrhosis.• An
evidence-based justification for bleeding risk assessment in patients with cirrhosis before …

Portal vein thrombosis (PVT) is an increasingly recognised complication of cirrhosis whose
incidence increases in parallel with the severity of cirrhosis. Several risk factors have been …

Portal vein thrombosis unrelated to solid malignancy is common in patients with cirrhosis,
but less frequently observed in patients without cirrhosis. Prompt diagnosis and …

The liver microcirculatory milieu, mainly composed of liver sinusoidal endothelial cells
(LSECs), hepatic stellate cells (HSCs) and hepatic macrophages, has an essential role in …

Disorders of the mesenteric, portal, and hepatic veins and mesenteric and hepatic arteries
have important clinical consequences and may lead to acute liver failure, chronic liver …

Patients with liver disease are at increased risks of both thrombotic and bleeding
complications. Many have atrial fibrillation (AF) or venous thromboembolism (VTE) …

Budd Chiari syndrome (BCS) is a diverse disease with regard to the site of obstruction, the
predisposing thrombophilic disorders and clinical presentation across the Asia-Pacific …

Patients with cirrhosis frequently acquire complex changes in their haemostatic system
including a decreased platelet count and decreased levels of various haemostatic proteins …

Patients with acute and chronic liver disease frequently acquire unique changes in
haemodynamic and haemostatic pathways that may result in life-threatening bleeding and …

The expression splanchnic vein thrombosis encompasses Budd-Chiari syndrome and portal
vein thrombosis. These disorders have common characteristics: they are both rare diseases …