Current advance of nanotechnology in diagnosis and treatment for malignant tumors

B Wang, S Hu, Y Teng, J Chen, H Wang, Y Xu… - … and Targeted Therapy, 2024 - nature.com
Cancer remains a significant risk to human health. Nanomedicine is a new multidisciplinary
field that is garnering a lot of interest and investigation. Nanomedicine shows great potential …

Biomaterials Facilitating Dendritic Cell‐Mediated Cancer Immunotherapy

H Dong, Q Li, Y Zhang, M Ding, Z Teng… - Advanced …, 2023 - Wiley Online Library
Dendritic cell (DC)‐based cancer immunotherapy has exhibited remarkable clinical
prospects because DCs play a central role in initiating and regulating adaptive immune …

Composite hydrogel for spatiotemporal lipid intervention of tumor milieu

J Ma, D Guo, X Ji, Y Zhou, C Liu, Q Li… - Advanced …, 2023 - Wiley Online Library
Induction of immunogenic cell death (ICD) plays crucial roles in cancer immunotherapy,
whereas its efficacy is severely compromised by redundant antioxidant defenses in cancer …

Multivalent glycosystems for human lectins

M Martínez-Bailén, J Rojo… - Chemical Society …, 2023 - pubs.rsc.org
Human lectins are involved in a wide variety of biological processes, both physiological and
pathological, which have attracted the interest of the scientific community working in the …

Nanotechnology‐Assisted RNA Delivery: From Nucleic Acid Therapeutics to COVID‐19 Vaccines

C Rinoldi, SS Zargarian, P Nakielski, X Li… - Small …, 2021 - Wiley Online Library
In recent years, the main quest of science has been the pioneering of the groundbreaking
biomedical strategies needed for achieving a personalized medicine. Ribonucleic acids …

Precise assembly of proteins and carbohydrates for next-generation biomaterials

L Li, G Chen - Journal of the American Chemical Society, 2022 - ACS Publications
The complexity and diversity of biomacromolecules make them a unique class of building
blocks for generating precise assemblies. They are particularly available to a new …

Nanovaccines for cancer immunotherapy: current knowledge and future perspectives

Y Wu, Z Zhang, Y Wei, Z Qian, X Wei - Chinese Chemical Letters, 2023 - Elsevier
Cancer immunotherapy harnesses the immune system to attack tumors and has received
extensive attention in recent years. Cancer vaccines as an important branch of …

CO-DELIVERY of glutamic acid-extended peptide antigen and imidazoquinoline TLR7/8 agonist via ionizable lipid nanoparticles induces protective anti-tumor …

T Ye, Z Zhong, F Cappellesso, K Deswarte, Y Chen… - Biomaterials, 2024 - Elsevier
Cancer vaccines aim at generating cytotoxic CD8+ T cells that kill cancer cells and confer
durable tumor regression. Hereto, CD8+ peptide epitopes should be presented by antigen …

Synthetic glycomacromolecules of defined valency, absolute configuration, and topology distinguish between human lectins

M Hartweg, Y Jiang, G Yilmaz, CM Jarvis, HVT Nguyen… - JACS Au, 2021 - ACS Publications
Carbohydrate-binding proteins (lectins) play vital roles in cell recognition and signaling,
including pathogen binding and innate immunity. Thus, targeting lectins, especially those on …

Enhancing immunity with nanomedicine: employing nanoparticles to harness the immune system

CT Perciani, LY Liu, L Wood, SA MacParland - ACS nano, 2020 - ACS Publications
The failure of immune responses to vaccines and dysfunctional immune responses to viral
infection, tumor development, or neoantigens lead to chronic viral infection, tumor …