P Cossart, A Helenius - Cold Spring Harbor perspectives …, 2014 - cshperspectives.cshlp.org
Of the many pathogens that infect humans and animals, a large number use cells of the host organism as protected sites for replication. To reach the relevant intracellular compartments …
Abstract mRNA vaccines have become a versatile technology for the prevention of infectious diseases and the treatment of cancers. In the vaccination process, mRNA formulation and …
JC Saiz, Á Vázquez-Calvo, AB Blázquez… - Frontiers in …, 2016 - frontiersin.org
Since the beginning of this century, humanity has been facing a new emerging, or re- emerging, virus threat almost every year: West Nile, Influenza A, avian flu, dengue …
mRNA vaccines have been revolutionary in combating the COVID-19 pandemic in the past two years. They have also become a versatile tool for the prevention of infectious diseases …
A Akinc, G Battaglia - Cold Spring Harbor perspectives …, 2013 - cshperspectives.cshlp.org
In this article, we briefly review the endocytic pathways used by cells, pointing out their defining characteristics and highlighting physical limitations that may direct the …
Flaviviruses are emerging arthropod-borne pathogens that cause life-threatening diseases such as yellow fever, dengue, West Nile encephalitis, tick-borne encephalitis, Kyasanur …
The first responders of human antiviral immunity are components of the intrinsic immune response that reside within each and every one of our cells. This cell-autonomous arsenal …
R Jia, F Xu, J Qian, Y Yao, C Miao… - Cellular …, 2014 - Wiley Online Library
Members of the interferon‐induced transmembrane (IFITM) protein family inhibit the entry of a wide range of viruses. Viruses often exploit the endocytosis pathways to invade host cells …
Effective treatment of retinal diseases with adeno-associated virus (AAV)-mediated gene therapy is highly dependent on the proportion of successfully transduced cells. However …