Lysosomes serve as the cellular recycling centre and are filled with numerous hydrolases
that can degrade most cellular macromolecules. Lysosomal membrane permeabilization …

Of the many pathogens that infect humans and animals, a large number use cells of the host
organism as protected sites for replication. To reach the relevant intracellular compartments …

Abstract mRNA vaccines have become a versatile technology for the prevention of infectious
diseases and the treatment of cancers. In the vaccination process, mRNA formulation and …

Since the beginning of this century, humanity has been facing a new emerging, or re-
emerging, virus threat almost every year: West Nile, Influenza A, avian flu, dengue …

mRNA vaccines have been revolutionary in combating the COVID-19 pandemic in the past
two years. They have also become a versatile tool for the prevention of infectious diseases …

In this article, we briefly review the endocytic pathways used by cells, pointing out their
defining characteristics and highlighting physical limitations that may direct the …

Flaviviruses are emerging arthropod-borne pathogens that cause life-threatening diseases
such as yellow fever, dengue, West Nile encephalitis, tick-borne encephalitis, Kyasanur …

The first responders of human antiviral immunity are components of the intrinsic immune
response that reside within each and every one of our cells. This cell-autonomous arsenal …

Members of the interferon‐induced transmembrane (IFITM) protein family inhibit the entry of
a wide range of viruses. Viruses often exploit the endocytosis pathways to invade host cells …

Effective treatment of retinal diseases with adeno-associated virus (AAV)-mediated gene
therapy is highly dependent on the proportion of successfully transduced cells. However …