The Principle of Cortical Development and Evolution
Z Yang - Neuroscience bulletin, 2024 - Springer
Human's robust cognitive abilities, including creativity and language, are made possible, at
least in large part, by evolutionary changes made to the cerebral cortex. This paper reviews …
least in large part, by evolutionary changes made to the cerebral cortex. This paper reviews …
The transcription factor Zfp503 promotes the D1 MSN identity and represses the D2 MSN identity
Z Shang, L Yang, Z Wang, Y Tian, Y Gao… - Frontiers in Cell and …, 2022 - frontiersin.org
The striatum is primarily composed of two types of medium spiny neurons (MSNs)
expressing either D1-or D2-type dopamine receptors. However, the fate determination of …
expressing either D1-or D2-type dopamine receptors. However, the fate determination of …
Taltirelin induces TH expression by regulating TRHR and RARα in medium spiny neurons
K Zhu, L Meng, J Luo, T Wen, L Dan, Z Wang… - Journal of Translational …, 2024 - Springer
Taltirelin, an orally effective thyrotropin-releasing hormone analog, significantly improves
motor impairments in rat models of Parkinson's disease (PD) and enhances dopamine …
motor impairments in rat models of Parkinson's disease (PD) and enhances dopamine …
High order expression dependencies finely resolve cryptic states and subtypes in single cell data
Single cells are typically typed by clustering into discrete locations in reduced dimensional
transcriptome space. Here we introduce Stator, a data-driven method that identifies cell …
transcriptome space. Here we introduce Stator, a data-driven method that identifies cell …
[HTML][HTML] The SoxE factor Sox9 is selectively expressed in indirect pathway striatal projection neurons and regulates synaptogenesis
X Song, X Li, X Pan, H Yang, K Wang, T Yang… - Fundamental …, 2024 - Elsevier
Striatum, as the largest structure of the basal ganglia, serves as a center for information
transmission and is critical for motor function and reward perception. However, the genetic …
transmission and is critical for motor function and reward perception. However, the genetic …
ELAVL3 regulates splicing of RNAs encoding synaptic signaling proteins in D1 and D2 striatal medium spiny neurons.
The neuronal RNA-binding protein (RBP) family nELAVL regulates key neuronal processes
by binding directly to target RNA transcripts. In this study, we demonstrate that ELAVL3 is the …
by binding directly to target RNA transcripts. In this study, we demonstrate that ELAVL3 is the …
Déficits développementaux du circuit striatal chez des modèles murins de la maladie de Huntington
M Lebouc - 2023 - theses.hal.science
La maladie de Huntington (MH) est une maladie neurodégénérative héréditaire causée par
une mutation sur le gène Huntingtine (Htt). Bien que les symptômes, caractérisés …
une mutation sur le gène Huntingtine (Htt). Bien que les symptômes, caractérisés …