Overview of platelet physiology: its hemostatic and nonhemostatic role in disease pathogenesis

K Ghoshal, M Bhattacharyya - The Scientific World Journal, 2014 - Wiley Online Library
Platelets are small anucleate cell fragments that circulate in blood playing crucial role in
managing vascular integrity and regulating hemostasis. Platelets are also involved in the …

Diabetes and atherosclerosis: epidemiology, pathophysiology, and management

JA Beckman, MA Creager, P Libby - Jama, 2002 - jamanetwork.com
ContextComplications of atherosclerosis cause most morbidity and mortality in patients with
diabetes mellitus. Despite the frequency and severity of disease, proven medical therapy …

Diabetes and vascular disease: pathophysiology, clinical consequences, and medical therapy: Part I

MA Creager, TF Lüscher… - Circulation, 2003 - Am Heart Assoc
oxygen species (such as superoxide anion) that inactivate NO to form peroxynitrite. 27, 28
Hyperglycemia may initiate this process by increasing superoxide anion production via the …

Guidelines on diabetes, pre-diabetes, and cardiovascular diseases: executive summary: The Task Force on Diabetes and Cardiovascular Diseases of the European …

L Rydén, E Standl, M Bartnik… - European heart …, 2007 - academic.oup.com
Task Forces, expert groups, or consensus panels. The chosen experts in these writing
panels are asked to provide disclosure statements of all relationships they may have, which …

Postprandial hyperglycemia and diabetes complications: is it time to treat?

A Ceriello - Diabetes, 2005 - Am Diabetes Assoc
Increasing evidence suggests that the postprandial state is a contributing factor to the
development of atherosclerosis. In diabetes, the postprandial phase is characterized by a …

Cardiometabolic aspects of the polycystic ovary syndrome

HS Randeva, BK Tan, MO Weickert, K Lois… - Endocrine …, 2012 - academic.oup.com
Polycystic ovary syndrome (PCOS) is the most common endocrine disorder amongst women
of reproductive age and is associated with various metabolic perturbations, in addition to …

Hyperglycemia and acute coronary syndrome: a scientific statement from the American Heart Association Diabetes Committee of the Council on Nutrition, Physical …

P Deedwania, M Kosiborod, E Barrett, A Ceriello… - Circulation, 2008 - Am Heart Assoc
Hyperglycemia is common and associated with markedly increased mortality rates in
patients hospitalized with acute coronary syndromes (ACS). Despite the fact that several …

The role of oxidative stress in diabetic complications

DM Niedowicz, DL Daleke - Cell biochemistry and biophysics, 2005 - Springer
The morbidity and mortality associated with diabetes is the result of the myriad complications
related to the disease. One of the most explored hypotheses to explain the onset of …

Biomarkers of diabetes-associated oxidative stress and antioxidant status in young diabetic patients with or without subclinical complications

P Martín-Gallán, A Carrascosa, M Gussinyé… - Free Radical Biology …, 2003 - Elsevier
The aims of the study were to ascertain the potential role of oxidative stress in the onset of
disease-related pathophysiological complications in young type 1 diabetes patients …

Endothelial dysfunction and pathogenesis of diabetic angiopathy

CDA Stehouwer, J Lambert, AJM Donker… - Cardiovascular …, 1997 - academic.oup.com
Abstract Objective and Methods: To review, from the clinical perspective, the contribution of
dysfunction of the vascular endothelium to the pathogenesis of diabetic micro-and …