The fibroblast growth factor (FGF) family is composed of 18 secreted signaling proteins
consisting of canonical FGFs and endocrine FGFs that activate four receptor tyrosine …

Growth factors belonging to the FGF family play important roles in tissue and organ repair
after trauma. In this review, I discuss the regulation by FGFs of the aspects of cellular …

Transected axons fail to regrow across anatomically complete spinal cord injuries (SCI) in
adults. Diverse molecules can partially facilitate or attenuate axon growth during …

Fibrosis is a pathological condition that is characterized by the replacement of dead or
damaged tissue with a nonfunctional, mechanically aberrant scar, and fibrotic pathologies …

Sustained epidermal Wnt/β-catenin signalling expands the stem cell compartment and
induces ectopic hair follicles (EFs). This is accompanied by extensive fibroblast proliferation …

Abstract Fibroblast growth factor-2 (FGF2) has multiple roles in cutaneous wound healing
but its natural low stability prevents the development of its use in skin repair therapies. Here …

This review elaborates the idea that organ regeneration derives from specific evolutionary
histories of vertebrates. Regenerative ability depends on genomic regulation of genes …

Background Previous human and animal studies have demonstrated the ability of
exogenously administered basic fibroblast growth factor (FGF2) to act as an antifibrotic …

Syndecans are transmembrane heparan sulfate proteoglycans, with roles in development,
tumorigenesis and inflammation, and growing evidence for involvement in tissue …

Heart valve disease is a growing problem worldwide. Though very common in older adults,
the mechanisms behind the development of the disease aren't well understood, and at …