DNA-based label-free electrochemical biosensors: From principles to applications

X Hai, Y Li, C Zhu, W Song, J Cao, S Bi - TrAC Trends in Analytical …, 2020 - Elsevier
As a kind of excellent biomaterials, deoxyribonucleic acids (DNAs) have been employed to
build a variety of biosensors via the interactions between DNAs and biomolecules or …

Electrochemistry of nucleic acids

E Palecek, M Bartosik - Chemical Reviews, 2012 - ACS Publications
Large differences between the DPP responses of ss-and dsDNAs (Figure 4B) suggest that
the double-helical structure of the dsDNA is not significantly disturbed at the DME surface …

Homogeneous electrochemical strategy for human telomerase activity assay at single-cell level based on T7 exonuclease-aided target recycling amplification

X Liu, W Li, T Hou, S Dong, G Yu, F Li - Analytical chemistry, 2015 - ACS Publications
As an important biomarker for early cancer diagnostics and a valuable therapeutic target,
telomerase has attracted extensive attention concerning its detection and monitoring …

Ultrasensitive assay for telomerase activity via self-enhanced electrochemiluminescent ruthenium complex doped metal–organic frameworks with high emission …

C Xiong, W Liang, Y Zheng, Y Zhuo, Y Chai… - Analytical …, 2017 - ACS Publications
Here, an ultrasensitive “off–on” electrochemiluminescence (ECL) biosensor was proposed
for the determination of telomerase activity by using a self-enhanced ruthenium …

[PDF][PDF] Label‐free ultrasensitive detection of human telomerase activity using porphyrin‐functionalized graphene and electrochemiluminescence technique

L Wu, J Wang, L Feng, J Ren, W Wei, X Qu - Advanced Materials, 2012 - researchgate.net
Human telomerase is a ribonucleoprotein that adds the TTAGGG repeats on the telomeric
ends of chromosomal DNA, it protects chromosomes from fusion, recombination and …

Sensitive electrochemical detection of telomerase activity using spherical nucleic acids gold nanoparticles triggered mimic-hybridization chain reaction enzyme-free …

WJ Wang, JJ Li, K Rui, PP Gai, JR Zhang… - Analytical …, 2015 - ACS Publications
We report an electrochemical sensor for telomerase activity detection based on spherical
nucleic acids gold nanoparticles (SNAs AuNPs) triggered mimic-hybridization chain reaction …

Assays for human telomerase activity: progress and prospects

X Zhou, D Xing - Chemical Society reviews, 2012 - pubs.rsc.org
Human telomerase is a ribonucleoprotein complex that functions as a telomere terminal
transferase by adding multiple TTAGGG hexamer repeats using its integral RNA as the …

A new approach to amplified telomerase detection with polyvalent oligonucleotide nanoparticle conjugates

G Zheng, WL Daniel, CA Mirkin - Journal of the American …, 2008 - ACS Publications
We report a new assay for human telomerase activity that relies on polyvalent
oligonucleotide nanoparticle conjugates as diagnostic probes and amplification units. Gold …

Sensitive and bidirectional detection of urine telomerase based on the four detection-color states of difunctional gold nanoparticle probe

R Duan, B Wang, T Zhang, Z Zhang, S Xu… - Analytical …, 2014 - ACS Publications
Telomerase, a valuable biomarker, is highly correlated with the development of most of
human cancers. Here, we develop a bidirectional strategy for telomerase activity detection …

Electrochemical detection of telomerase in cancer cells based on the in-situ formation of streptavidin-biotin-DNA-biotin networks for signal amplification

L Liu, D Wu, S Zhen, K Lu, X Yi, Z Sun - Sensors and Actuators B: Chemical, 2021 - Elsevier
This work reports on a simple and sensitive electrochemical strategy for the detection of
telomerase extracted from HeLa cells. It was based on the signal amplification of in-situ …