The liver is a unique organ with an abundant regenerative capacity. Therefore, partial
hepatectomy (PHx) or partial liver transplantation (PLTx) can be safely performed. Liver …

Background: Liver resection represents the first choice of treatment for primary and
secondary liver malignancies, offering the patient the best chance of long-term survival. The …

Objectives: To assess safety and outcomes of the novel 2-stage hepatectomy, Associating
Liver Partition and Portal Vein Ligation for Staged Hepatectomy (ALPPS), using an …

Immigration, cheap air travel, and globalization are all factors contributing to a worldwide
spread of hepatitis B virus (HBV) and hepatitis C virus (HCV) infection. End‐stage chronic …

The ability of hepatocytes to enter the cell cycle and regenerate the liver after tissue loss
provides an in vivo model to study the regulation of proliferation and organ regeneration …

Liver failure is a dreaded and often fatal complication that sometimes follows a partial
hepatic resection. This article reviews the definition, incidence, pathogenesis, risk factors …

Nonalcoholic fatty liver disease is a relatively new hepatic sequela of obesity and type 2
diabetes. The pathogenesis of liver injury and disease progression in nonalcoholic fatty liver …

Non-alcoholic fatty liver disease (NAFLD) is the most common chronic liver disease in the
Western world, and it persists at a high prevalence. NAFLD is characterised by the …

Background & Aims: Portal fibrosis and linkage is a key feature of progressive disease in
nonalcoholic steatohepatitis (NASH), but not simple steatosis. It is underappreciated and …

Since its discovery twenty-five years ago, the fat-derived hormone leptin has provided a
revolutionary framework for studying the physiological role of adipose tissue as an …