Despite the exceptional progress in breast cancer pathogenesis, prognosis, diagnosis, and
treatment strategies, it remains a prominent cause of female mortality worldwide …

In recent years, there has been a significant surge in reports on the health-promoting
benefits of winter cherry (Withania somnifera), also known as Ashwagandha. Its current …

The spread of protein aggregates during disease progression is a common theme
underlying many neurodegenerative diseases. The microtubule-associated protein tau has …

Recent advances have greatly improved our understanding of the molecular mechanisms
behind atherosclerosis pathogenesis. However, there is still a need to systematize this data …

Ischemic stroke can cause secondary myelin damage in the white matter distal to the
primary injury site. The contribution of astrocytes during secondary demyelination and the …

Proprotein convertase subtilisin/kexin type 9 (PCSK9) has evolved as a pivotal enzyme in
lipid metabolism and a revolutionary therapeutic target for hypercholesterolemia and its …

Permanent hearing loss affects more than 5% of the world's population, yet there are no
nondevice therapies that can protect or restore hearing. Delivery of therapeutics to the …

Vesicular stomatitis virus (VSV) exhibits a remarkably robust and pantropic infectivity,
mediated by its coat protein, VSV-G. Using this property, recombinant forms of VSV and VSV …

Apolipoprotein E (APOE) genotype is the major genetic risk factor for Alzheimer disease
(AD); the ε4 allele increases risk and the ε2 allele is protective. In the central nervous system …

Vascular smooth muscle cells (VSMCs) are the stromal cells of the vascular wall, continually
exposed to mechanical signals and biochemical components generated in the blood …