Human longevity is a complex phenotype resulting from the combinations of context-
dependent gene-environment interactions that require analysis as a dynamic process in a …

The genetic origin of the three common variants of the human apolipoprotein E (apoE)
protein, known as E2, E3 and E4, was understood in 1981, and since the mid 1980s these …

Apolipoprotein E (APOE) genotype determines Alzheimer's disease (AD) susceptibility, with
the APOE ε4 allele being an established risk factor for late‐onset AD. The ApoE lipidation …

Lipoproteins in the central nervous system (CNS) are not incorporated from the blood but
are formed mainly by glial cells within the CNS. In addition, cholesterol in the CNS is …

The deposition of amyloid β-protein (Aβ) fibrils into plaques within the brain parenchyma
and along cerebral blood vessels is a hallmark of Alzheimer's disease (AD). Aβ42 oligomers …

We examined the combined effect of plasma lipids/hypertension and apolipoprotein E
(APOE) genotype on cognitive function in elderly individuals. Plasma concentrations of high …

The apolipoprotein E epsilon 4 (ApoE4) allele is the strongest genetic risk factor for
Alzheimer's disorder (AD) and is associated with semantic and episodic memory deficits …

There are many incredible biological psychology textbooks out there, which explain all the
intricacies of the subject and discuss the current developments of human brain science. So …

Apolipoprotein E (ApoE) is a protein that plays an important role in the transport of fatty acids
and cholesterol and in cellular signaling. On the surface of the cells, ApoE lipoparticles bind …

Alzheimer's disease (AD) has long been characterized primarily by extracellular deposition
of Aβ protein. It is a genetically intricate neurodegenerative disorder. Presenilins …