Metastasis is the hallmark of cancer that is responsible for the greatest number of cancer-
related deaths. Yet, it remains poorly understood. The continuous evolution of cancer …

Tumour metastasis, the movement of tumour cells from a primary site to progressively
colonize distant organs, is a major contributor to the deaths of cancer patients. Therapeutic …

Patterns of genomic evolution between primary and metastatic breast cancer have not been
studied in large numbers, despite patients with metastatic breast cancer having dismal …

Background Metastatic breast cancer (MBC) treatment has changed substantially over time,
but we do not know whether survival post-metastasis has improved at the population level …

Approximately 0.5 million people worldwide die from metastatic breast cancer (mBC) every
year. This manuscript provides an overview on the status of mBC in several regions of the …

Breast tumor recurrence and metastasis represent the main causes of cancer-related death
in women, and treatments are still lacking. Here, we define the lipogenic enzyme acetyl-CoA …

Triple-negative breast cancer (TNBC), characterized by the absence or low expression of
estrogen receptor (ER), progesterone receptor (PR), and human epidermal growth factor …

Human mesenchymal stem/stromal cells (hMSCs) have been shown to support breast
cancer cell proliferation and metastasis, partly through their secretome. hMSCs have a …

Purpose In the last 25 years new treatment options in breast cancer have evolved. We
wanted to determine whether the survival of; patients with metastatic breast cancer have …

Despite advances in breast cancer treatment, it remains the leading cause of cancer-related
death in women worldwide. In this context, microRNAs have emerged as potential …