Lipopolysaccharide-induced model of neuroinflammation: mechanisms of action, research application and future directions for its use

A Skrzypczak-Wiercioch, K Sałat - Molecules, 2022 - mdpi.com
Despite advances in antimicrobial and anti-inflammatory therapies, inflammation and its
consequences still remain a significant problem in medicine. Acute inflammatory responses …

Mesenchymal stem cells reverse EMT process through blocking the activation of NF-κB and Hedgehog pathways in LPS-induced acute lung injury

K Xiao, W He, W Guan, F Hou, P Yan, J Xu… - Cell death & …, 2020 - nature.com
Acute lung injury (ALI) is a pulmonary disorder, which can result in fibrosis of the lung
tissues. Recently, mesenchymal stem cell (MSC) has become a novel therapeutic method …

MicroRNAs and cytokines as potential predictive biomarkers for COVID-19 disease progression

HA Mohamed, AE Abdelkafy, RMM Khairy… - Scientific reports, 2023 - nature.com
Host microRNAs can influence the cytokine storm associated SARS-CoV-2 infection and
proposed as biomarkers for COVID-19 disease. In the present study, serum MiRNA-106a …

microRNAs associated with the pathogenesis and their role in regulating various signaling pathways during Mycobacterium tuberculosis infection

KS Davuluri, DS Chauhan - Frontiers in Cellular and Infection …, 2022 - frontiersin.org
Despite more than a decade of active study, tuberculosis (TB) remains a serious health
concern across the world, and it is still the biggest cause of mortality in the human …

Radix Glycyrrhizae extract and licochalcone a exert an anti-inflammatory action by direct suppression of toll like receptor 4

M Cai, Y Xu, B Deng, JB Chen, TF Chen… - Journal of …, 2023 - Elsevier
Abstract Ethnopharmacological relevance Radix Glycyrrhizae (GL), a herbal medicine that is
widely available, has shown advantages for a variety of inflammatory diseases. Toll like …

Hypoxia-inducible ubiquitin specific peptidase 13 contributes to tumor growth and metastasis via enhancing the toll-like receptor 4/myeloid differentiation primary …

S Gao, T Chen, L Li, X Liu, Y Liu, J Zhao… - Frontiers in Cell and …, 2020 - frontiersin.org
Hepatocellular carcinoma (HCC) is one of the leading causes of cancer death worldwide.
The activation of the toll-like receptor 4/myeloid differentiation primary response gene …

N-palmitoyl-D-glucosamine, a natural monosaccharide-based glycolipid, inhibits TLR4 and prevents LPS-induced inflammation and neuropathic pain in mice

M Iannotta, C Belardo, MC Trotta, FA Iannotti… - International Journal of …, 2021 - mdpi.com
Toll-like receptors (TLRs) are key receptors through which infectious and non-infectious
challenges act with consequent activation of the inflammatory cascade that plays a critical …

Sophoricoside attenuates lipopolysaccharide-induced acute lung injury by activating the AMPK/Nrf2 signaling axis

Y Wu, S Zeng, B Wan, Y Wang, H Sun, G Liu… - International …, 2021 - Elsevier
Sophoricoside (SOP), an isoflavone glycoside isolated from seed of Sophora japonica L.,
has been reported to have various pharmacological activities, including anti-cancer, anti …

[HTML][HTML] Itaconate ameliorates methicillin-resistant Staphylococcus aureus-induced acute lung injury through the Nrf2/ARE pathway

G Liu, Y Wu, S Jin, J Sun, BB Wan, J Zhang… - Annals of …, 2021 - ncbi.nlm.nih.gov
Background Methicillin-resistant Staphylococcus aureus (MRSA) are a critical predisposing
factor of sepsis in the clinic. As a product of human energy metabolism and immune …

Combination Effect of Three Main Constituents From Sarcandra glabra Inhibits Oxidative Stress in the Mice Following Acute Lung Injury: A Role of MAPK-NF-κB …

CP Liu, JX Liu, J Gu, F Liu, JH Li, S Wu, Q Wu… - Frontiers in …, 2021 - frontiersin.org
Caffeoylquinic acids, coumarins and dicaffeoyl derivatives are considered to be three kinds
of the most abundant bioactive components in Sarcandra glabra, an anti-inflammatory herb …