Gallbladder cancer (GBC) is characterized by a highly invasive nature and a poor prognosis,
with adenocarcinoma being the main histological subtype. According to statistical data …

Consistently, the high metastasis of cancer cells is the bottleneck in the process of tumor
treatment. In this process of metastasis, a pivotal role is executed by epithelial …

Background and aims Distant metastasis is a major cause of deaths in patients with
colorectal cancer (CRC), which is partly due to lack of robust metastasis-predictive …

Glioblastoma multiforme (GBM) is a lethal, therapy-resistant brain cancer consisting of
numerous tumor cell subpopulations, including stem-like glioma-initiating cells (GICs), which …

Long noncoding RNAs (lncRNAs) are important regulatory molecules in various biological
and pathological processes, including cancer development. We have previously shown that …

The transforming growth factor β (TGFβ) pathway plays critical roles during cancer cell
epithelial-mesenchymal transition (EMT) and metastasis. SMAD7 is both a transcriptional …

Epithelial-to-mesenchymal transition (EMT) and its reverse process, mesenchymal-to-
epithelial transition (MET), play important roles in embryogenesis, stem cell biology, and …

Abstract microRNAs (miRNAs) can regulate epithelial-mesenchymal transition (EMT)
through transcription factors, however, little is known whether EMT transcription factors can …

The epithelial-mesenchymal transition (EMT) imparts metastatic competence on otherwise
non-metastatic cancer cells through decreased inter-cellular adhesions, increased migratory …

While it is known that miR-203 is frequently downregulated in many types of human cancer,
little is known regarding its expression and functional role in colorectal cancer (CRC). In this …