Climate change imposes a severe threat to agricultural systems, food security, and human
nutrition. Meanwhile, efforts in crop and livestock gene editing have been undertaken to …

The human population is growing, and as a result we need to produce more food whilst
reducing the impact of farming on the environment. Selective breeding and genomic …

CRISPR-Cas9 is a promising technology for genome editing. Here we use Cas9 nuclease-
induced double-strand break DNA (DSB) at the UROS locus to model and correct congenital …

Generation of genetically uniform non-human primates may help to establish animal models
for primate biology and biomedical research. In this study, we have successfully cloned …

CRISPR/Cas9-based genome editing can easily generate knockout mouse models by
disrupting the gene sequence, but its efficiency for creating models that require either …

Globally, there are approximately one billion beef cattle, and compared with poultry and
swine, beef cattle have the poorest conversion efficiency of feed to meat. However, these …

Clustered regularly interspaced short palindromic repeats (CRISPR) and the CRISPR-
associated gene Cas9 represent an invaluable system for the precise editing of genes in …

Genetic improvement of cattle around the globe has been, and will continue to be, an
important driver of animal agriculture sustainability. There are several reproductive and …

Many studies have been conducted to improve economically important livestock traits such
as feed efficiency and muscle growth. Genome editing technologies represent a major …

Nuclear localization of HIPPO-YAP fusion proteins has been implicated in supratentorial
ependymoma development. Here, unexpectedly, we find that liquid–liquid phase separation …