Acute myeloid leukemia: a comprehensive review and 2016 update

I De Kouchkovsky, M Abdul-Hay - Blood cancer journal, 2016 - nature.com
Acute myeloid leukemia (AML) is the most common acute leukemia in adults, with an
incidence of over 20 000 cases per year in the United States alone. Large chromosomal …

An update of current treatments for adult acute myeloid leukemia

H Dombret, C Gardin - Blood, The Journal of the American …, 2016 - ashpublications.org
Recent advances in acute myeloid leukemia (AML) biology and its genetic landscape
should ultimately lead to more subset-specific AML therapies, ideally tailored to each …

Acute myeloid leukaemia in adult patients: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up

M Heuser, Y Ofran, N Boissel, SB Mauri… - Annals of …, 2020 - annalsofoncology.org
Acute myeloid leukaemia (AML) incidence is age dependent, rising markedly in patients
aged! 60 years. Ageing of the European population may therefore contribute to the reported …

Haploidentical vs identical-sibling transplant for AML in remission: a multicenter, prospective study

Y Wang, QF Liu, LP Xu, KY Liu… - Blood, The Journal …, 2015 - ashpublications.org
The effects of HLA-identical sibling donor (ISD) hematopoietic stem cell transplantation
(HSCT) on adults with intermediate-or high-risk acute myeloid leukemia (AML) in the first …

Hematopoietic stem cell transplantation for patients with AML in first complete remission

JJ Cornelissen, D Blaise - Blood, The Journal of the American …, 2016 - ashpublications.org
Postremission therapy in patients with acute myeloid leukemia (AML) may consist of
continuing chemotherapy or transplantation using either autologous or allogeneic stem …

Diagnosis and management of acute myeloid leukemia in adults: recommendations from an international expert panel, on behalf of the European LeukemiaNet

H Döhner, EH Estey, S Amadori… - Blood, The Journal …, 2010 - ashpublications.org
In 2003, an international working group last reported on recommendations for diagnosis,
response assessment, and treatment outcomes in acute myeloid leukemia (AML). Since that …

Refinement of cytogenetic classification in acute myeloid leukemia: determination of prognostic significance of rare recurring chromosomal abnormalities among 5876 …

D Grimwade, RK Hills, AV Moorman… - Blood, The Journal …, 2010 - ashpublications.org
Diagnostic karyotype provides the framework for risk-stratification schemes in acute myeloid
leukemia (AML); however, the prognostic significance of many rare recurring cytogenetic …

Therapeutic advances in acute myeloid leukemia

A Burnett, M Wetzler, B Löwenberg - Journal of clinical oncology, 2011 - ascopubs.org
The choice of treatment approach and outcome in acute myeloid leukemia (AML) depends
on the age of the patient. In younger patients, arbitrarily defined as being younger than 60 …

Mutations and treatment outcome in cytogenetically normal acute myeloid leukemia

RF Schlenk, K Döhner, J Krauter… - … England Journal of …, 2008 - Mass Medical Soc
Background Mutations occur in several genes in cytogenetically normal acute myeloid
leukemia (AML) cells: the nucleophosmin gene (NPM1), the fms-related tyrosine kinase 3 …

Hematopoietic stem cell transplantation: a global perspective

A Gratwohl, H Baldomero, M Aljurf, MC Pasquini… - Jama, 2010 - jamanetwork.com
Context Hematopoietic stem cell transplantation (HSCT) requires significant infrastructure.
Little is known about HSCT use and the factors associated with it on a global level …