Neurodegenerative diseases (NDs) such as Alzheimer disease (AD), Parkinson disease
(PD), and Huntington disease (HD) represent a major socio-economic challenge in view of …

There is significant evidence that, in living systems, free radicals and other reactive oxygen
and nitrogen species play a double role, because they can cause oxidative damage and …

Redox-dependent processes influence most cellular functions, such as differentiation,
proliferation, and apoptosis. Mitochondria are at the center of these processes, as …

Mitochondria form intricate networks through fission and fusion events. Here, we identify
mitochondrial dynamics proteins of 49 and 51 kDa (MiD49 and MiD51, respectively) …

Mitochondrial dysfunction is a prominent feature of Alzheimer's disease (AD) neurons. In this
study, we explored the involvement of an abnormal mitochondrial dynamics by investigating …

Diabetic nephropathy (DN) is the most common cause of end-stage kidney disease
worldwide, and is associated with increased morbidity and mortality in patients with both …

In response to cellular and environmental stresses, mitochondria undergo morphology
transitions regulated by dynamic processes of membrane fusion and fission. These events of …

Mammalian photoreceptors aggregate numerous mitochondria, organelles chiefly for energy
production, in the ellipsoid region immediately adjacent to the light-sensitive outer segment …

Mitochondria play a key role in oncogenesis and constitute one of the most important targets
for cancer treatments. Although the most effective way to deliver drugs to mitochondria is by …

The ability to directly visualize nanoscopic cellular structures and their spatial relationship in
all three dimensions will greatly enhance our understanding of molecular processes in cells …