Oxytocin, neural plasticity, and social behavior

RC Froemke, LJ Young - Annual Review of Neuroscience, 2021 - annualreviews.org
Oxytocin regulates parturition, lactation, parental nurturing, and many other social behaviors
in both sexes. The circuit mechanisms by which oxytocin modulates social behavior are …

The oxytocin receptor: from intracellular signaling to behavior

B Jurek, ID Neumann - Physiological reviews, 2018 - journals.physiology.org
The many facets of the oxytocin (OXT) system of the brain and periphery elicited nearly
25,000 publications since 1930 (see, as listed in PubMed), which revealed central roles for …

Psychedelics reopen the social reward learning critical period

R Nardou, E Sawyer, YJ Song, M Wilkinson… - Nature, 2023 - nature.com
Psychedelics are a broad class of drugs defined by their ability to induce an altered state of
consciousness,. These drugs have been used for millennia in both spiritual and medicinal …

Music as a coevolved system for social bonding

PE Savage, P Loui, B Tarr, A Schachner… - Behavioral and Brain …, 2021 - cambridge.org
Why do humans make music? Theories of the evolution of musicality have focused mainly
on the value of music for specific adaptive contexts such as mate selection, parental care …

Molecular and network-level mechanisms explaining individual differences in autism spectrum disorder

AM Buch, PE Vértes, J Seidlitz, SH Kim… - Nature …, 2023 - nature.com
The mechanisms underlying phenotypic heterogeneity in autism spectrum disorder (ASD)
are not well understood. Using a large neuroimaging dataset, we identified three latent …

Decoding molecular and cellular heterogeneity of mouse nucleus accumbens

R Chen, TR Blosser, MN Djekidel, J Hao… - Nature …, 2021 - nature.com
The nucleus accumbens (NAc) plays an important role in regulating multiple behaviors, and
its dysfunction has been linked to many neural disorders. However, the molecular, cellular …

Social trauma engages lateral septum circuitry to occlude social reward

L Li, R Durand-de Cuttoli, AV Aubry, CJ Burnett… - Nature, 2023 - nature.com
In humans, traumatic social experiences can contribute to psychiatric disorders. It is
suggested that social trauma impairs brain reward function such that social behaviour is no …

[HTML][HTML] Mechanisms underlying microbial-mediated changes in social behavior in mouse models of autism spectrum disorder

M Sgritta, SW Dooling, SA Buffington, EN Momin… - Neuron, 2019 - cell.com
Currently, there are no medications that effectively treat the core symptoms of Autism
Spectrum Disorder (ASD). We recently found that the bacterial species Lactobacillus (L.) …

Signalling pathways in autism spectrum disorder: mechanisms and therapeutic implications

CC Jiang, LS Lin, S Long, XY Ke, K Fukunaga… - Signal transduction and …, 2022 - nature.com
Autism spectrum disorder (ASD) is a prevalent and complex neurodevelopmental disorder
which has strong genetic basis. Despite the rapidly rising incidence of autism, little is known …

Social touch promotes interfemale communication via activation of parvocellular oxytocin neurons

Y Tang, D Benusiglio, A Lefevre, L Hilfiger… - Nature …, 2020 - nature.com
Oxytocin (OT) is a great facilitator of social life but, although its effects on socially relevant
brain regions have been extensively studied, OT neuron activity during actual social …