Pediatric brain tumours: Lessons from the immune microenvironment

B Yao, A Delaidelli, H Vogel, PH Sorensen - Current Oncology, 2023 - mdpi.com
In spite of recent advances in tumour molecular subtyping, pediatric brain tumours (PBTs)
remain the leading cause of cancer-related deaths in children. While some PBTs are …

Radio-pathomic approaches in pediatric neuro-oncology: Opportunities and challenges

AM Familiar, A Mahtabfar… - Neuro-Oncology …, 2023 - academic.oup.com
With medical software platforms moving to cloud environments with scalable storage and
computing, the translation of predictive artificial intelligence (AI) models to aid in clinical …

[HTML][HTML] Blood gene expression biomarkers of response to anti-TNF drugs in pediatric inflammatory bowel diseases before initiation of treatment

S Salvador-Martín, G Rubbini, P Vellosillo… - Biomedicine & …, 2024 - Elsevier
Background/aims Changes in gene expression profiles among individuals with inflammatory
bowel diseases (IBDs) could potentially influence the responsiveness to anti-TNF treatment …

Transcriptomics-based characterization of the immuno-stromal microenvironment in pediatric low-grade glioma

M Körner, M Spohn, U Schüller, M Bockmayr - Oncoimmunology, 2024 - Taylor & Francis
Immunologic treatment options are uncommon in low-grade gliomas, although such
therapies might be beneficial for inoperable and aggressive cases. Knowledge of the …

[HTML][HTML] Advances in the Repurposing and Blood–Brain Barrier Penetrance of Drugs in Pediatric Brain Tumors

JS Rechberger, SA Toll, S Biswas, HB You, WD Chow… - Cancers, 2025 - mdpi.com
Central nervous system (CNS) tumors are the leading cause of cancer-related mortality in
children, with prognosis remaining dismal for some of these malignancies. Though the past …

Immunotherapy for pediatric low-grade gliomas

IF Pollack, J Felker, SC Frederico, I Raphael… - Child's Nervous …, 2024 - Springer
Pediatric low-grade gliomas (pLGGs) are the most common brain tumor types affecting
children. Although gross-total resection remains the treatment of choice, many tumors are …

Immunogenomics is on the Way Up: Combining immune-system science, omics, and various computational algorithms might produce success where advanced …

M May - Inside Precision Medicine, 2024 - liebertpub.com
 Mike May is a freelance writer and editor with more than 30 years of experience. He
earned an MS in biological engineering from the University of Connecticut and a PhD in …