A de Morree, TA Rando - Nature Reviews Molecular Cell Biology, 2023 - nature.com
Adult stem cells are important for mammalian tissues, where they act as a cell reserve that supports normal tissue turnover and can mount a regenerative response following acute …
AJ De Micheli, EJ Laurilliard, CL Heinke… - Cell reports, 2020 - cell.com
Muscle regeneration relies on the regulation of muscle stem cells (MuSCs) through paracrine signaling interactions. We analyzed muscle regeneration in mice using single-cell …
Skeletal muscle regeneration is a finely tuned process involving the activation of various cellular and molecular processes. Satellite cells, the stem cells of skeletal muscle, are …
Skeletal muscles are essential for vital functions such as movement, postural support, breathing, and thermogenesis. Muscle tissue is largely composed of long, postmitotic …
Skeletal muscle is a complex tissue containing tissue resident muscle stem cells (satellite cells)(MuSCs) important for postnatal muscle growth and regeneration. Quantitative analysis …
NA Dumont, YX Wang, J Von Maltzahn, A Pasut… - Nature medicine, 2015 - nature.com
Dystrophin is expressed in differentiated myofibers, in which it is required for sarcolemmal integrity, and loss-of-function mutations in the gene that encodes it result in Duchenne …
Muscle stem cells, termed satellite cells, are crucial for skeletal muscle growth and regeneration. In healthy adult muscle, satellite cells are quiescent but poised for activation …
Skeletal muscle mass, function, and repair capacity all progressively decline with aging, restricting mobility, voluntary function, and quality of life. Skeletal muscle repair is facilitated …
P Feige, CE Brun, M Ritso, MA Rudnicki - Cell stem cell, 2018 - cell.com
Muscle stem cells, or satellite cells, are required for skeletal muscle maintenance, growth, and repair. Following satellite cell activation, several factors drive asymmetric cell division to …