Nanomedicines have created a paradigm shift in healthcare. Yet fundamental barriers still
exist that prevent or delay the clinical translation of nanomedicines. Critical hurdles …

The pH-sensitive polymers have attained significant attention in the arena of targeted drug
delivery (TDD) because of their exceptional capability to respond to alteration in pH in …

Lipid nanoparticles (LNPs) currently dominate the RNA delivery landscape; however their
limited diffusivity hampers targeted tissue dissemination, and, hence, their capacity for …

Nanotechnology has attained significant attention from researchers in past decades due to
its numerous advantages, such as biocompatibility, biodegradability, and improved stability …

Predictive performance assays are crucial for the development and approval of
nanomedicines and their bioequivalent successors. At present, there are no established …

The main objective of this study is the evaluation of the use of a synthetic membrane,
Nuclepore, as a model for permeation studies through sublingual mucosa. The permeability …

Controlled drug delivery technology has matured for more than 70 years, starting from a
twice-a-day oral formulation to 6 month long-acting injectable formulations. Further …

Nanoparticle physicochemical properties have received great attention in optimizing the
performance of nanoparticles for biomedical applications. For example, surface …

Understanding both the physicochemical and biological interactions of nanoparticles is
mandatory for the biomedical application of nanomaterials. By binding proteins …

The molecular mechanism of the formation of protein corona by the interaction of gold
nanorods (AuNRs) with fibrinogen and transferrin was studied by spectroscopic methods …