Neurodegeneration in glaucoma: progression and calcium-dependent intracellular mechanisms

SD Crish, DJ Calkins - Neuroscience, 2011 - Elsevier
Glaucoma is an age-related optic neuropathy involving sensitivity to ocular pressure. The
disease is now seen increasingly as one of the central nervous system, as powerful new …

The coma in glaucoma: Retinal ganglion cell dysfunction and recovery

LE Fry, E Fahy, V Chrysostomou, F Hui, J Tang… - Progress in retinal and …, 2018 - Elsevier
Retinal ganglion cell (RGC) degeneration causes vision loss in patients with glaucoma, and
this has been generally considered to be irreversible due to RGC death. We question this …

[HTML][HTML] Photopic negative response versus pattern electroretinogram in early glaucoma

D Preiser, WA Lagreze, M Bach… - … ophthalmology & visual …, 2013 - arvojournals.org
Purpose.: Photopic negative response (PhNR) and pattern electroretinogram (PERG) are
electrophysiological markers of retinal ganglion cell function; both are reduced in glaucoma …

Monitoring retinal morphologic and functional changes in mice following optic nerve crush

Y Liu, CM McDowell, Z Zhang… - … & visual science, 2014 - iovs.arvojournals.org
Purpose.: We characterized the morphologic and functional changes in optic nerve crushed
mice and evaluated electroretinogram (ERG) responses as tools to monitor retinal ganglion …

Ganglion cell loss in early glaucoma, as assessed by photopic negative response, pattern electroretinogram, and spectral-domain optical coherence tomography

B Cvenkel, M Sustar, D Perovšek - Documenta Ophthalmologica, 2017 - Springer
Purpose To evaluate discrimination ability of pattern electroretinography (PERG) and
photopic negative response (PhNR) between early glaucoma and healthy controls, and their …

Electrophysiology and glaucoma: current status and future challenges

M Bach, CM Poloschek - Cell and tissue research, 2013 - Springer
Visual electrophysiology allows non-invasive monitoring of the function of most processing
stages along the visual pathway. Here, we consider which of the available methods provides …

[HTML][HTML] Pattern electroretinogram in ocular hypertension, glaucoma suspect and early manifest glaucoma eyes: a systematic review and meta-analysis

GG Afflitto, TH Chou, SS Swaminathan, F Aiello… - Ophthalmology …, 2023 - Elsevier
Topic To provide standardized confidence limits of the transient pattern electroretinogram
(tPERG) P50 and N95 and steady state pattern electroretinogram (ssPERG) amplitudes in …

[HTML][HTML] The pattern of retinal ganglion cell dysfunction in Leber hereditary optic neuropathy

A Majander, AG Robson, C João, GE Holder… - Mitochondrion, 2017 - Elsevier
Leber inherited optic neuropathy (LHON) is characterized by subacute bilateral loss of
central vision due to dysfunction and loss of retinal ganglion cells (RGCs). Comprehensive …

Retinal ganglion cell functional plasticity and optic neuropathy: a comprehensive model

V Porciatti, LM Ventura - Journal of Neuro-ophthalmology, 2012 - journals.lww.com
The clinical management of glaucoma and optic neuropathies has traditionally focused on
stages of the diseases at which there are congruent losses of visual function and optic nerve …

Prediction of glaucoma severity using parameters from the electroretinogram

M Sarossy, J Crowston, D Kumar, A Weymouth, Z Wu - Scientific reports, 2021 - nature.com
Glaucoma is an optic neuropathy that results in the progressive loss of retinal ganglion cells
(RGCs), which are known to exhibit functional changes prior to cell loss. The …