The ability of neurotrophic factors to regulate developmental neuronal survival and adult
nervous system planticity suggests the use of these molecuales to treat neurodegeneration …

▪ Abstract The field of neurotrophic factor pharmacology emerged during the past decade
with the discovery that these proteins can counteract neuronal atrophy and death in the adult …

Evidence for the presence of the vitamin D receptor in brain implies this vitamin may have
some function in this organ. This study investigates whether vitamin D3 acts during brain …

Neurotrophins and other neurotrophic factors have been shown to support the survival and
differentiation of many neuronal populations of the central and peripheral nervous system …

Nerve growth factor is an essential neurotrophic factor required for the growth and
maintenance of cutaneous sensory nerves. In the skin, keratinocytes are a significant source …

We have proposed that elevating levels of nerve growth factor (NGF) in the CNS is a rational
strategy for treating certain neurodegenerative disorders. The present studies were …

Neurotrophins have highly potent biological effects preventing neuronal death and
promoting neurite outgrowth; however, like most proteins they do not have optimal …

The nerve growth factor (NGF) receptors p75 LNGR and TrkA are expressed by thymic
epithelial cells. Presumably, the NGF-TrkA system is involved in the paracrine …

Neonatal rat cortical astrocytes in primary culture synthesize and secrete nerve growth factor
(NGF). Treatment of astrocytes with interleukin‐1β (IL‐1) or the protein kinase C (PKC) …

Interactions between sympathetic and parasympathetic nerves are important in regulating
visceral target function. Sympathetic nerves are closely apposed to, and form functional …