Viruses of archaea represent one of the most enigmatic parts of the virosphere. Most of the
characterized archaeal viruses infect extremophilic hosts and display remarkable diversity of …

This review presents a personal account of research on archaeal viruses and describes
many new viral species and families, demonstrating that viruses of Archaea constitute a …

The Archaea—and their viruses—remain the most enigmatic of life's three domains. Once
thought to inhabit only extreme environments, archaea are now known to inhabit diverse …

The genomes of all organisms abound with various cis-regulatory elements, which control
gene activity. Transcriptional enhancers are a key group of such elements in eukaryotes and …

Abstract The Type VI-D CRISPR-Cas system employs an RNA-guided RNase Cas13d with
minimal targeting constraints to combat viral infections. This CRISPR system contains …

For cellular fitness and survival, gene expression levels need to be regulated in response to
a wealth of cellular and environmental signals. TFs (transcription factors) execute a large …

Sulfolobus spindle-shaped virus 1 is the only UV-inducible member of the virus family
Fuselloviridae. Originally isolated from Saccharolobus shibatae B12, it can also infect …

Little is known about how archaeal viruses perturb the transcription machinery of their hosts.
Here we provide the first example of an archaeo-viral transcription factor that directly targets …

The chromatinisation of DNA by nucleoid‐associated proteins (NAPs) in archaea 'formats'
the genome structure in profound ways, revealing both striking differences and analogies to …

The ability of organisms to sense and respond to their environment is essential to their
survival. This is no different for members of the third domain of life, the Archaea. Archaea are …