Safety and tolerability of available urate-lowering drugs: a critical review
Introduction: Urate-lowering therapy (ULT) is the cornerstone of gout management, which is
a widespread chronic illness characterized by hyperuricemia, arthropathy, tophus …
a widespread chronic illness characterized by hyperuricemia, arthropathy, tophus …
Agents for the treatment of gout: current advances and future perspectives
X Zeng, Y Liu, Y Fan, D Wu, Y Meng… - Journal of Medicinal …, 2023 - ACS Publications
Gout is characterized by hyperuricemia and the deposition of monosodium urate (MSU)
crystals around joints. Despite the availability of several drugs on the market, its treatment …
crystals around joints. Despite the availability of several drugs on the market, its treatment …
[HTML][HTML] The British Society for Rheumatology guideline for the management of gout
M Hui, A Carr, S Cameron, G Davenport… - …, 2017 - academic.oup.com
Gout is the most common cause of inflammatory arthritis worldwide. In UK general practice,
the overall prevalence has increased from 1.4% in 1999 to 2.49% in 2012 [1], despite the …
the overall prevalence has increased from 1.4% in 1999 to 2.49% in 2012 [1], despite the …
[HTML][HTML] Benzbromarone in the treatment of gout
Background Benzbromarone is a uricosuric drug that has been used in the treatment of gout
over the last 30 years. Due to its potent inhibition of the dominant apical (luminal) urate …
over the last 30 years. Due to its potent inhibition of the dominant apical (luminal) urate …
Anti-hyperuricemic effects of astaxanthin by regulating xanthine oxidase, adenosine deaminase and urate transporters in rats
Y Le, X Zhou, J Zheng, F Yu, Y Tang, Z Yang, G Ding… - Marine drugs, 2020 - mdpi.com
This study was designed to investigate the effects and underlying mechanisms of
Astaxanthin (AST) on high-fructose-induced hyperuricemia (HUA) from the perspectives of …
Astaxanthin (AST) on high-fructose-induced hyperuricemia (HUA) from the perspectives of …
Potential applications and preliminary mechanism of action of dietary polyphenols against hyperuricemia: A review
H Zhu, D Song, X Zhao - Food Bioscience, 2021 - Elsevier
Hyperuricemia (HUA), a condition triggered by high serum uric acid (UA) levels in blood,
seems to be the main, if not the only, risk factor for gout. The condition is also an …
seems to be the main, if not the only, risk factor for gout. The condition is also an …
Novel urate transporter 1 (URAT1) inhibitors: a review of recent patent literature (2016–2019)
Y Dong, T Zhao, W Ai, WA Zalloum… - Expert Opinion on …, 2019 - Taylor & Francis
Introduction: Human urate transporter 1 (URAT1), which is an influx transporter protein, is
located at the apical surface of renal tubular cells and presumed to be the major transporter …
located at the apical surface of renal tubular cells and presumed to be the major transporter …
[HTML][HTML] Sunflower head enzymatic hydrolysate relives hyperuricemia by inhibiting crucial proteins (xanthine oxidase, adenosine deaminase, uric acid transporter1) …
G Liu, X Chen, X Lu, J Zhao, X Li - Journal of Functional Foods, 2020 - Elsevier
To exploit an effective natural medicine for hyperuricemia, this research investigated the anti-
hyperuricemic efficacy and mechanism of sunflower head enzymatic hydrolysate (SHEH) …
hyperuricemic efficacy and mechanism of sunflower head enzymatic hydrolysate (SHEH) …
Actions of water extract from Cordyceps militaris in hyperuricemic mice induced by potassium oxonate combined with hypoxanthine
T Yong, M Zhang, D Chen, O Shuai, S Chen… - Journal of …, 2016 - Elsevier
Ethnopharmacological relevance Cordyceps militaris was recorded in the classic traditional
Chinese medicine book with the main functions of “protecting liver and enhancing kidney …
Chinese medicine book with the main functions of “protecting liver and enhancing kidney …
Antihyperuricemia and antigouty arthritis effects of Persicaria capitata herba in mice
CL Zhang, JJ Zhang, QF Zhu, HY Guan, YX Yang, X He… - Phytomedicine, 2021 - Elsevier
Background: Hyperuricemia (HUA) is an important risk factor for gout, renal dysfunction and
cardiovascular diseases. The whole plant of Persicaria capitata (Buch.-Ham. ex D. Don) H …
cardiovascular diseases. The whole plant of Persicaria capitata (Buch.-Ham. ex D. Don) H …