[HTML][HTML] Innate immune response to monkeypox virus infection: mechanisms and immune escape
R Parnian, F Heydarifard, FS Mousavi… - Journal of Innate …, 2024 - karger.com
Background: The reemergence of monkeypox virus (Mpox, formerly monkeypox) in 2022 in
non-endemic countries has raised significant concerns for global health due to its high …
non-endemic countries has raised significant concerns for global health due to its high …
Vaccinia virus-mediated oncolytic immunotherapy: emerging strategies for gastrointestinal cancer treatment at dawn
H Jin, Y Zhao, F Huang, Z Hong, XY Jia, H Wang… - Virology, 2024 - Elsevier
Oncolytic vaccinia virus (VVs) based immunotherapy is a rapidly developing treatment for
gastrointestinal (GI) cancers. Conventional treatments, such as chemotherapy, radiotherapy …
gastrointestinal (GI) cancers. Conventional treatments, such as chemotherapy, radiotherapy …
ATM inhibition exploits checkpoint defects and ATM-dependent double strand break repair in TP53-mutant glioblastoma
DJ Laverty, SK Gupta, GA Bradshaw, AS Hunter… - Nature …, 2024 - nature.com
Determining the balance between DNA double strand break repair (DSBR) pathways is
essential for understanding treatment response in cancer. We report a method for …
essential for understanding treatment response in cancer. We report a method for …
Vaccinia Virus: Mechanisms Supporting Immune Evasion and Successful Long-Term Protective Immunity
J Hsu, S Kim, N Anandasabapathy - Viruses, 2024 - mdpi.com
Vaccinia virus is the most successful vaccine in human history and functions as a protective
vaccine against smallpox and monkeypox, highlighting the importance of ongoing research …
vaccine against smallpox and monkeypox, highlighting the importance of ongoing research …
Vaccinia virus Tiantan strain blocks host antiviral innate immunity and programmed cell death by disrupting gene expression
C Wu, Z Zhang, Z Li, R Li, S Huo, H Li, R Lu… - Biosafety and …, 2024 - mednexus.org
The vaccinia virus Tiantan (VTT) is widely utilized as a smallpox vaccine in China and holds
significant importance in the prevention of diseases stemming from poxvirus infections …
significant importance in the prevention of diseases stemming from poxvirus infections …
Highly Multiplexed Proteomic Analysis of HCMV-Infected Dendritic Cells Reveals Global Manipulation of Adaptive Immunity and Host Restriction of Viral Replication
L Kerr-Jones, L Soday, N Cwyfan-Hughes, X Wang… - bioRxiv, 2024 - biorxiv.org
Human cytomegalovirus (HCMV) is a clinically significant herpesvirus and a paradigm for
pathogen-mediated immune-evasion. Its broad tropism includes antigen-presenting cells …
pathogen-mediated immune-evasion. Its broad tropism includes antigen-presenting cells …
[PDF][PDF] The role of FBXO22 in antiviral immunity and its antagonism by orthopoxviruses.
P Parija - 2024 - openresearch.surrey.ac.uk
Cullin-RING E3 ubiquitin ligases (CRLs) are a major family of ubiquitin ligases. CRLs are
formed by a scaffold protein (Cullin) that forms a multimeric complex with an E2 ubiquitin …
formed by a scaffold protein (Cullin) that forms a multimeric complex with an E2 ubiquitin …