Thyroid disease and lipids

LH Duntas - Thyroid, 2002 - liebertpub.com
The composition and the transport of lipoproteins are seriously disturbed in thyroid diseases.
Overt hypothyroidism is characterized by hypercholesterolaemia and a marked increase in …

Hypothyroidism and atherosclerosis

AR Cappola, PW Ladenson - The Journal of Clinical …, 2003 - academic.oup.com
This autopsy finding of diffuse atherosclerosis in a 58-yrold woman was published as an
appendix to William Ord's classical description of the syndrome of myxedema. Soon …

The Colorado thyroid disease prevalence study

GJ Canaris, NR Manowitz, G Mayor… - Archives of internal …, 2000 - jamanetwork.com
Context The prevalence of abnormal thyroid function in the United States and the
significance of thyroid dysfunction remain controversial. Systemic effects of abnormal thyroid …

Hypothyroidism as a risk factor for cardiovascular disease

B Biondi, I Klein - Endocrine, 2004 - Springer
The cardiovascular risk in patients with hypothyroidism is related to an increased risk of
functional cardiovascular abnormalities and to an increased risk of atherosclerosis. The …

Cardiovascular and atherogenic aspects of subclinical hypothyroidism

GJ Kahaly - Thyroid, 2000 - liebertpub.com
Subclinical hypothyroidism (SH) is common, especially among elderly women. There is no
clear evidence to date that SH causes clinical heart disease. However, mild thyroid gland …

The treatment of subclinical hypothyroidism is seldom necessary

JW Chu, LM Crapo - The Journal of Clinical Endocrinology & …, 2001 - academic.oup.com
Subclinical hypothyroidism (SH) is a common disorder with a prevalence ranging from 1–
10% of the adult population in most community studies (1–14). The risk of developing SH …

Hypothyroidism and risk of cardiovascular disease

ZM Gluvic, SS Zafirovic, MM Obradovic… - Current …, 2022 - ingentaconnect.com
Thyroid hormones (TH) have a significant impact on cellular oxidative metabolism. Besides
that, they maintain vascular homeostasis by positive effects on endothelial and vascular …

Thyroid hormones as a disease modifier and therapeutic target in nonalcoholic steatohepatitis

EK Wirth, T Puengel, J Spranger… - Expert Review of …, 2022 - Taylor & Francis
Introduction Nonalcoholic fatty liver disease (NAFLD) is the most common cause of chronic
liver disease worldwide and closely interconnected to the metabolic syndrome. Liver …

Systemic thyroid hormone status during levothyroxine therapy in hypothyroidism: a systematic review and meta-analysis

EA McAninch, KB Rajan, CH Miller… - The Journal of Clinical …, 2018 - academic.oup.com
Context The standard of care for overt hypothyroidism is levothyroxine (LT4) at doses that
normalize serum TSH levels. Whether this approach universally restores thyroid hormone …

Lipid profile in subclinical hypothyroidism: is L-thyroxine substitution beneficial?

Z Efstathiadou, S Bitsis, HJ Milionis… - European journal of …, 2001 - academic.oup.com
Objective The significance of dyslipidemia in subclinical hypothyroidism (SH) and the effect
of thyroid substitution on lipids remain controversial. The present study aimed to assess the …