International Union of Basic and Clinical Pharmacology. CX. Classification of receptors for 5-hydroxytryptamine; pharmacology and function
5-HT receptors expressed throughout the human body are targets for established
therapeutics and various drugs in development. Their diversity of structure and function …
therapeutics and various drugs in development. Their diversity of structure and function …
[HTML][HTML] The serotonergic system and cognitive function
D Švob Štrac, N Pivac, D Mück-Šeler - Translational neuroscience, 2016 - degruyter.com
Symptoms of cognitive dysfunction like memory loss, poor concentration, impaired learning
and executive functions are characteristic features of both schizophrenia and Alzheimer's …
and executive functions are characteristic features of both schizophrenia and Alzheimer's …
Cellular and molecular actions of methylene blue in the nervous system
Methylene Blue (MB), following its introduction to biology in the 19th century by Ehrlich, has
found uses in various areas of medicine and biology. At present, MB is the first line of …
found uses in various areas of medicine and biology. At present, MB is the first line of …
The serotonergic system in ageing and Alzheimer's disease
JJ Rodríguez, HN Noristani, A Verkhratsky - Progress in neurobiology, 2012 - Elsevier
Alzheimer's disease (AD) is one of the major neurodegenerative diseases that deteriorates
cognitive functions and primarily affects associated brain regions involved in learning and …
cognitive functions and primarily affects associated brain regions involved in learning and …
Effect of idalopirdine as adjunct to cholinesterase inhibitors on change in cognition in patients with Alzheimer disease: three randomized clinical trials
Importance New therapeutic approaches for Alzheimer disease (AD) are needed. Objective
To assess whether idalopirdine, a selective 5-hydroxytryptamine-6 receptor antagonist, is …
To assess whether idalopirdine, a selective 5-hydroxytryptamine-6 receptor antagonist, is …
The role of G protein-coupled receptors in the pathology of Alzheimer's disease
A Thathiah, B De Strooper - Nature Reviews Neuroscience, 2011 - nature.com
G protein-coupled receptors (GPCRs) are involved in numerous key neurotransmitter
systems in the brain that are disrupted in Alzheimer's disease (AD). GPCRs also directly …
systems in the brain that are disrupted in Alzheimer's disease (AD). GPCRs also directly …
Methylene blue and Alzheimer's disease
The relationship between methylene blue (MB) and Alzheimer's disease (AD) has recently
attracted increasing scientific attention since it has been suggested that MB may slow down …
attracted increasing scientific attention since it has been suggested that MB may slow down …
A role for the 5-HT1A, 5-HT4 and 5-HT6 receptors in learning and memory
MV King, CA Marsden, KCF Fone - Trends in pharmacological sciences, 2008 - cell.com
The serotonergic system is implicated in the neurobiological control of learning and memory,
both in healthy individuals and pathological disorders, although the underlying mechanisms …
both in healthy individuals and pathological disorders, although the underlying mechanisms …
Serotonergic system, cognition, and BPSD in Alzheimer's disease
Abstract Behavioral and Psychological Symptoms of Dementia (BPSD), present in almost
90% of patients with Alzheimer's Disease (AD), cause extensive impairment leading to …
90% of patients with Alzheimer's Disease (AD), cause extensive impairment leading to …
The role of 5 HT6-receptor antagonists in Alzheimer's disease: an update
R Khoury, N Grysman, J Gold, K Patel… - Expert opinion on …, 2018 - Taylor & Francis
Introduction: Despite recent advances in Alzheimer's disease (AD) research, no
breakthrough treatments have been discovered. Cholinesterase inhibitors and the NMDA …
breakthrough treatments have been discovered. Cholinesterase inhibitors and the NMDA …