Lennox-Gastaut syndrome: a comprehensive review

AA Asadi-Pooya - Neurological Sciences, 2018 - Springer
Lennox-Gastaut syndrome (LGS) is considered an epileptic encephalopathy and is defined
by a triad of multiple drug-resistant seizure types, a specific EEG pattern showing bursts of …

Corpus callosotomy outcomes in pediatric patients: a systematic review

D Graham, MM Tisdall, D Gill - Epilepsia, 2016 - Wiley Online Library
Objective Corpus callosotomy is a palliative neurosurgical treatment for patients with either
generalized or multifocal refractory epilepsy and injurious drop attacks. This report aims to …

Motor control and neural plasticity through interhemispheric interactions

N Takeuchi, Y Oouchida, SI Izumi - Neural plasticity, 2012 - Wiley Online Library
The corpus callosum, which is the largest white matter structure in the human brain,
connects the 2 cerebral hemispheres. It plays a crucial role in maintaining the independent …

Magnetic resonance imaging-guided laser interstitial thermal therapy for epilepsy: systematic review of technique, indications, and outcomes

BE Youngerman, AV Save, GM McKhann - Neurosurgery, 2020 - journals.lww.com
BACKGROUND For patients with focal drug-resistant epilepsy (DRE), surgical resection of
the epileptogenic zone (EZ) may offer seizure freedom and benefits for quality of life. Yet …

[PDF][PDF] Pharmacoresistant epilepsy: from pathogenesis to current and emerging therapies

S Pati, AV Alexopoulos - Cleve Clin J Med, 2010 - researchgate.net
Almost one-third of people with epilepsy continue to have seizures despite appropriate
antiepileptic drug treatment, placing them at considerable risk of cognitive and psychosocial …

Resting-state activity in development and maintenance of normal brain function

CE Pizoli, MN Shah, AZ Snyder… - Proceedings of the …, 2011 - National Acad Sciences
One of the most intriguing recent discoveries concerning brain function is that intrinsic
neuronal activity manifests as spontaneous fluctuations of the blood oxygen level …

Rates and predictors of seizure outcome after corpus callosotomy for drug-resistant epilepsy: a meta-analysis

AY Chan, JD Rolston, B Lee, S Vadera… - Journal of neurosurgery, 2018 - thejns.org
OBJECTIVE Corpus callosotomy is a palliative surgery for drug-resistant epilepsy that
reduces the severity and frequency of generalized seizures by disconnecting the two …

[HTML][HTML] Vagus nerve stimulation vs. corpus callosotomy in the treatment of Lennox–Gastaut syndrome: a meta-analysis

G Lancman, M Virk, H Shao, M Mazumdar… - Seizure, 2013 - Elsevier
PURPOSE: Lennox–Gastaut syndrome (LGS) is an epileptogenic disorder that arises in
childhood and is typically characterized by multiple seizure types, slow spike-and-wave …

Seizure outcomes in nonresective epilepsy surgery: an update

DJ Englot, H Birk, EF Chang - Neurosurgical review, 2017 - Springer
In approximately 30% of patients with epilepsy, seizures are refractory to medical therapy,
leading to significant morbidity and increased mortality. Substantial evidence has …

Corpus callosotomy performed with laser interstitial thermal therapy

JL Roland, SHA Akbari, A Salehi, MD Smyth - Journal of neurosurgery, 2019 - thejns.org
OBJECTIVE Corpus callosotomy is a palliative procedure that is effective at reducing seizure
burden in patients with medically refractory epilepsy. The procedure is traditionally …