In 2007, an association of single nucleotide polymorphisms (SNPs) in the fat mass and
obesity-associated (FTO) gene region with body mass index (BMI) and risk of obesity was …

Candidate gene and genome-wide association studies have led to the discovery of nine loci
involved in Mendelian forms of obesity and 58 loci contributing to polygenic obesity. These …

As we enter the 21st century, a new era of nutrition in the prevention and treatment of
disease emerges. Clinical nutrition involves the integration of diet, genetics, environment …

Understanding why we eat and the motivational factors driving food choices is important for
addressing the epidemics of obesity, diabetes, and cardiovascular disease. Eating behavior …

Meta-analyses of population-based genome-wide association studies (GWAS) in adults
have recently led to the detection of new genetic loci for obesity. Here we aimed to discover …

Obesity has dramatically increased during the last decades and is currently one of the most
serious global health problems. We present a hypothesis that obesity is a neuro-behavioral …

Snacking is often presumed to contribute to obesity, but to date, studies have not
demonstrated such a causal relationship, probably because a clear definition of snacking is …

Objective Many confirmed genetic loci for obesity are expressed in regions of the brain that
regulate energy intake and reward‐seeking behavior. Whether these loci contribute to the …

The dysfunction of melanocortin signaling has been associated with obesity, given the
important role in the regulation of energy homeostasis, food intake, satiety and body weight …

Obesity is one of the leading causes of preventable death in the United States, second only
to smoking. The annual number of deaths attributed to obesity is estimated to be as high as …