Atherosclerosis is the main risk factor for cardiovascular disease (CVD), which is the leading
cause of mortality worldwide. Atherosclerosis is initiated by endothelium activation and …

Atherosclerosis (AS) is the major form of cardiovascular disease and the leading cause of
morbidity and mortality in countries around the world. Atherosclerosis combines the …

Haemodynamic forces influence the functional properties of vascular endothelium.
Endothelial cells (ECs) have a variety of receptors, which sense flow and transmit …

Background Experimental studies suggest that low wall shear stress (WSS) promotes
plaque development and high WSS is associated with plaque destabilization. We …

Atherosclerotic plaques are found at distinct locations in the arterial system, despite the
exposure to systemic risk factors of the entire vascular tree. From the study of arterial …

The heterogeneity of plaque formation, the vascular remodelling response to plaque
formation, and the consequent phenotype of plaque instability attest to the extraordinarily …

Cardiovascular pathologies such as intracranial aneurysms (IAs) and atherosclerosis
preferentially localize to bifurcations and curvatures where hemodynamics are complex …

The objective of our session at the 2008 International Bio-Fluid Symposium and Workshop
was to review the state-of-the-art in image-based modeling of blood flow, and identify future …

Once plaques intrude into the lumen, the shear stress they are exposed to alters with
hitherto unknown consequences for plaque composition. We investigated the relationship …

Background—The purpose of this study was to analyze the in vivo distribution of absolute
wall shear stress (WSSabs) and oscillatory shear index (OSI) in the carotid bifurcation and to …