Diabetes mellitus: The linkage between oxidative stress, inflammation, hypercoagulability and vascular complications

CP Domingueti, LMSA Dusse… - Journal of Diabetes and …, 2016 - Elsevier
Background Vascular complications are the leading cause of morbidity and mortality among
patients with type 1 and type 2 diabetes mellitus. These vascular abnormalities result of a …

Exercise for prevention and relief of cardiovascular disease: prognoses, mechanisms, and approaches

D Tian, J Meng - Oxidative Medicine and Cellular Longevity, 2019 - Wiley Online Library
This review is aimed at summarizing the new findings about the multiple benefits of exercise
on cardiovascular disease (CVD). We pay attention to the prevalence and risk factors of …

Regular physical exercise training assists in preventing type 2 diabetes development: focus on its antioxidant and anti-inflammatory properties

E Teixeira-Lemos, S Nunes, F Teixeira… - Cardiovascular diabetology, 2011 - Springer
Diabetes mellitus has emerged as one of the main alarms to human health in the 21st
century. Pronounced changes in the human environment, behavior and lifestyle have …

Modulation of insulin sensitivity by exercise training: implications for cardiovascular prevention

G Iaccarino, D Franco, D Sorriento… - Journal of …, 2021 - Springer
The beneficial effects of physical activity on the cardiovascular system nowadays have
achieved the relevance of clinical evidence. In fact, several studies have documented the …

Hypercholesterolemia and microvascular dysfunction: interventional strategies

PA Stapleton, AG Goodwill, ME James, RW Brock… - Journal of …, 2010 - Springer
Hypercholesterolemia is defined as excessively high plasma cholesterol levels, and is a
strong risk factor for many negative cardiovascular events. Total cholesterol levels above …

Therapeutic options targeting oxidative stress, mitochondrial dysfunction and inflammation to hinder the progression of vascular complications of diabetes

JS Teodoro, S Nunes, AP Rolo, F Reis… - Frontiers in …, 2019 - frontiersin.org
Type 2 diabetes mellitus is a leading cause of morbidity and mortality worldwide, given its
serious associated complications. Despite constant efforts and intensive research, an …

Effects of sitagliptin treatment on dysmetabolism, inflammation, and oxidative stress in an animal model of type 2 diabetes (ZDF rat)

L Ferreira, E Teixeira-de-Lemos, F Pinto… - Mediators of …, 2010 - Wiley Online Library
The purpose of this paper is to evaluate the chronic effect of sitagliptin on metabolic profile,
inflammation, and redox status in the Zucker Diabetic Fatty (ZDF) rat, an animal model of …

Obesity: genes, brain, gut, and environment

UN Das - Nutrition, 2010 - Elsevier
Obesity, which is assuming alarming proportions, has been attributed to genetic factors,
hypothalamic dysfunction, and intestinal gut bacteria and an increase in the consumption of …

Regular physical exercise as a strategy to improve antioxidant and anti‐inflammatory status: Benefits in type 2 diabetes mellitus

E Teixeira de Lemos, J Oliveira… - Oxidative medicine …, 2012 - Wiley Online Library
Over the last 30 years the combination of both a sedentary lifestyle and excessive food
availability has led to a significant increase in the prevalence of obesity and aggravation of …

Benefits of exercise intervention in reducing neuropathic pain

JL Dobson, J McMillan, L Li - Frontiers in cellular neuroscience, 2014 - frontiersin.org
Peripheral neuropathy is a widespread and potentially incapacitating pathological condition
that encompasses more than 100 different forms and manifestations of nerve damage. The …